Gene

plxna3

ID

ZDB-GENE-070613-1

Name

plexin A3

Symbol

plxna3 Nomenclature History

Previous Names

set
sidetracked
vermicelli (1)
vmc (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Exhibits identical protein binding activity. Involved in embryonic skeletal joint morphogenesis and nervous system development. Localizes to membrane. Is expressed in fin; nervous system; otic vesicle; and post-vent region. Orthologous to human PLXNA3 (plexin A3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 7 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 17 figures from 11 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plxna3 Human Ortholog

No data available

Associated With plxna3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR002909	IPT domain
Domain	IPR013548	Plexin, cytoplasmic RasGAP domain
Domain	IPR016201	PSI domain
Domain	IPR041019	Plexin, TIG domain 1
Domain	IPR041362	Plexin, TIG domain 2
Domain	IPR046800	Plexin, cytoplasmic RhoGTPase-binding domain
Family	IPR031148	Plexin family
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily
Repeat	IPR002165	Plexin repeat