Gene

adgrb1a

ID

ZDB-GENE-060607-12

Name

adhesion G protein-coupled receptor B1a

Symbol

adgrb1a Nomenclature History

Previous Names

bai1a
si:ch211-80e15.1 (1)
wu:fq36h12 (1)
zmp:0000000766

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in glioblastoma multiforme. Is expressed in muscle; nervous system; and testis. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adgrb1a Human Ortholog

No data available

Associated With adgrb1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000203	GPS motif
Domain	IPR001879	GPCR, family 2, extracellular hormone receptor domain
Domain	IPR017981	GPCR, family 2-like, 7TM
Domain	IPR032471	GAIN domain, N-terminal
Domain	IPR043838	Adhesion G protein-coupled receptor B, N-terminal domain
Family	IPR000832	GPCR, family 2, secretin-like
Family	IPR008077	GPCR, family 2, brain-specific angiogenesis inhibitor
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Homologous_superfamily	IPR036445	GPCR family 2, extracellular hormone receptor domain superfamily
Homologous_superfamily	IPR046338	GAIN domain superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat

Domain Details Per Protein

Protein	Length	Adhesion G protein-coupled receptor B, N-terminal domain	GAIN domain, N-terminal	GAIN domain superfamily	GPCR, family 2, brain-specific angiogenesis inhibitor	GPCR, family 2, extracellular hormone receptor domain	GPCR family 2, extracellular hormone receptor domain superfamily	GPCR, family 2-like, 7TM	GPCR, family 2, secretin-like	GPS motif	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A0A8M3AQX5 InterPro	1598
UniProtKB:A0A8M9NZT5 InterPro	1514
UniProtKB:A0A8M3AQX9 InterPro	1554
UniProtKB:A0A2R8PX08 InterPro	1610
UniProtKB:A0A8M9PK78 InterPro	1519
UniProtKB:A0A8M3ATQ5 InterPro	1605
UniProtKB:A0A8M9PDS9 InterPro	1575
UniProtKB:A0A8M3B1X9 InterPro	1547
UniProtKB:E7F9S0 InterPro	1529
UniProtKB:A0A8M3AJE0 InterPro	1577
UniProtKB:A0A8M3AIF0 InterPro	1549
UniProtKB:A0A8M9P8H3 InterPro	1261
UniProtKB:A0A8M3B1X6 InterPro	1580
UniProtKB:A0A2R8PVQ8 InterPro	1585

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adgrb1a-203 (1) Ensembl	Havana	3497 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	adgrb1a-002 (1) Ensembl	Havana	1391 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations