Gene
nle1
- ID
- ZDB-GENE-050522-321
- Name
- notchless homolog 1 (Drosophila)
- Symbol
- nle1 Nomenclature History
- Previous Names
-
- fc12b09
- fc45f01
- wu:fc12b09
- wu:fc45f01
- zgc:110281 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be involved in Notch signaling pathway and ribosomal large subunit assembly. Predicted to localize to nucleolus. Is expressed in alar plate midbrain region; nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NLE1 (notchless homolog 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110281 (1 image)
- IMAGE:7155292 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001632 | G-protein, beta subunit |
| Domain | IPR012972 | NLE |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein, beta subunit | G-protein beta WD-40 repeat | NLE | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QDT3
|
476 |
Interactions and Pathways
No data available
Plasmids
No data available