Gene

cpt1a2b

ID

ZDB-GENE-050417-155

Name

carnitine palmitoyltransferase 1A2b

Symbol

cpt1a2b Nomenclature History

Previous Names

cpt1cb (1)
si:dkey-16p21.4
zgc:112484

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 73. Is expressed in EVL; periderm; and polster. Orthologous to human CPT1C (carnitine palmitoyltransferase 1C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:112484 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cpt1a2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
carnitine palmitoyltransferase I deficiency	Alliance	CPT deficiency, hepatic, type IA	255120

Associated With cpt1a2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032476	Carnitine O-palmitoyltransferase, N-terminal
Domain	IPR039551	Choline/carnitine acyltransferase domain
Family	IPR000542	Acyltransferase ChoActase/COT/CPT
Homologous_superfamily	IPR023213	Chloramphenicol acetyltransferase-like domain superfamily
Homologous_superfamily	IPR042231	Choline/Carnitine o-acyltransferase, domain 2
Homologous_superfamily	IPR042572	Carnitine o-acyltransferase, N-terminal

Domain Details Per Protein

Protein	Length	Acyltransferase ChoActase/COT/CPT	Carnitine o-acyltransferase, N-terminal	Carnitine O-palmitoyltransferase, N-terminal	Chloramphenicol acetyltransferase-like domain superfamily	Choline/carnitine acyltransferase domain	Choline/Carnitine o-acyltransferase, domain 2
UniProtKB:A0A8M9PFB6 InterPro	807
UniProtKB:A0A8M9PYA7 InterPro	393
UniProtKB:A0A8M9Q999 InterPro	409
UniProtKB:E7EYD4 InterPro	780
UniProtKB:A0A8M3B117 InterPro	394

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cpt1cb-202 (1) Ensembl	Havana	2541 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	cpt1cb-002 (1) Ensembl	Havana	858 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations