Gene

crata

ID

ZDB-GENE-040927-17

Name

carnitine O-acetyltransferase a

Symbol

crata Nomenclature History

Previous Names

hm:zeh0248
zeh0248
zgc:92317

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu2430 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With crata Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Neurodegeneration with brain iron accumulation 8	617917

Associated With crata Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR039551	Choline/carnitine acyltransferase domain
Family	IPR000542	Acyltransferase ChoActase/COT/CPT
Homologous_superfamily	IPR023213	Chloramphenicol acetyltransferase-like domain superfamily
Homologous_superfamily	IPR042231	Choline/Carnitine o-acyltransferase, domain 2