Gene
p2rx2
- ID
- ZDB-GENE-030319-2
- Name
- purinergic receptor P2X, ligand-gated ion channel, 2
- Symbol
- p2rx2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits extracellularly ATP-gated cation channel activity. Involved in ion transport. Predicted to localize to integral component of nuclear inner membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Is expressed in Rohon-Beard neurons and cranial ganglion. Orthologous to human P2RX2 (purinergic receptor P2X 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Appelbaum et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 41 | Alliance | Deafness, autosomal dominant 41 | 608224 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P2X2 purinoceptor | P2X purinoreceptor | P2X purinoreceptor extracellular domain superfamily |
|---|---|---|---|---|
|
UniProtKB:Q7SZL9
|
400 |
Interactions and Pathways
No data available
Plasmids
No data available