Gene

hoga1

ID
ZDB-GENE-040426-2242
Name
4-hydroxy-2-oxoglutarate aldolase 1
Symbol
hoga1 Nomenclature History
Previous Names
  • zgc:77082
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have 4-hydroxy-2-oxoglutarate aldolase activity. Predicted to be involved in glyoxylate catabolic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 3. Orthologous to human HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoga1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary hyperoxaluria type 3 Alliance Hyperoxaluria, primary, type III 613616
Associated With hoga1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020625 Schiff base-forming aldolase, active site
Family IPR002220 DapA-like
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel DapA-like Schiff base-forming aldolase, active site
UniProtKB:Q6NY77 324
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations