PUBLICATION
Pigment cell interactions and differential xanthophore recruitment underlying zebrafish stripe reiteration and Danio pattern evolution
- Authors
- Patterson, L.B., Bain, E.J., Parichy, D.M.
- ID
- ZDB-PUB-141107-2
- Date
- 2014
- Source
- Nature communications 5: 5299 (Journal)
- Registered Authors
- Patterson, Larissa
- Keywords
- none
- MeSH Terms
-
- Animals
- Biological Evolution*
- Body Patterning/genetics
- Body Patterning/physiology*
- Cell Communication/physiology*
- Cell Differentiation/physiology
- Female
- Gene Expression Regulation, Developmental/genetics
- Gene Expression Regulation, Developmental/physiology
- Macrophage Colony-Stimulating Factor/genetics
- Macrophage Colony-Stimulating Factor/physiology
- Male
- Melanocytes/cytology*
- Melanocytes/physiology
- Phenotype
- Pigmentation/physiology*
- Signal Transduction/genetics
- Signal Transduction/physiology
- Species Specificity
- Time Factors
- Zebrafish/anatomy & histology*
- Zebrafish/classification
- Zebrafish/physiology*
- PubMed
- 25374113 Full text @ Nat. Commun.
Citation
Patterson, L.B., Bain, E.J., Parichy, D.M. (2014) Pigment cell interactions and differential xanthophore recruitment underlying zebrafish stripe reiteration and Danio pattern evolution. Nature communications. 5:5299.
Abstract
Fishes have diverse pigment patterns, yet mechanisms of pattern evolution remain poorly understood. In zebrafish, Danio rerio, pigment-cell autonomous interactions generate dark stripes of melanophores that alternate with light interstripes of xanthophores and iridophores. Here, we identify mechanisms underlying the evolution of a uniform pattern in D. albolineatus in which all three pigment cell classes are intermingled. We show that in this species xanthophores differentiate precociously over a wider area, and that cis regulatory evolution has increased expression of xanthogenic Colony Stimulating Factor-1 (Csf1). Expressing Csf1 similarly in D. rerio has cascading effects, driving the intermingling of all three pigment cell classes and resulting in the loss of stripes, as in D. albolineatus. Our results identify novel mechanisms of pattern development and illustrate how pattern diversity can be generated when a core network of pigment-cell autonomous interactions is coupled with changes in pigment cell differentiation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping