Choi et al., 2018
- Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations.
Science advances
4:eaau0731
Full text @ Sci Adv
Marker Type | Symbol | Name |
---|---|---|
Gene | ccm2 | CCM2 scaffold protein |
Gene | map3k2 | mitogen-activated protein kinase kinase kinase 2 |