Burkhalter et al., 2019 - Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. The Journal of Clinical Investigation   130:2841-2855 Full text @ Journal of Clin. Invest.
Human Disease / Model Data (3 Records)
Human Disease Fish Environment Evidence Code
ciliopathy WT
WT
WT + MO1-cox5aa
chemical treatment: 3-(2,4-dichlorophenyl)-7-hydroxy-4H-chromen-4-one
chemical treatment: rotenone
standard conditions
TAS
TAS
TAS
mitochondrial metabolism disease WT
WT
chemical treatment: rotenone
chemical treatment: 3-(2,4-dichlorophenyl)-7-hydroxy-4H-chromen-4-one
TAS
TAS
visceral heterotaxy WT + MO1-cox5aa
WT + MO1-mtrr
WT + MO1-osbpl1a
WT + MO1-phka2
WT + MO4-tafazzin
WT
WT
standard conditions
standard conditions
standard conditions
standard conditions
standard conditions
chemical treatment: 3-(2,4-dichlorophenyl)-7-hydroxy-4H-chromen-4-one
chemical treatment: rotenone
TAS
TAS
TAS
TAS
TAS
TAS
TAS