Gene
exoc5
- ID
- ZDB-GENE-080204-126
- Name
- exocyst complex component 5
- Symbol
- exoc5 Nomenclature History
- Previous Names
-
- sec10 (1)
- zgc:175220
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits protein self-association. Involved in several processes, including melanosome transport; photoreceptor cell maintenance; and photoreceptor cell outer segment organization. Predicted to localize to exocyst. Orthologous to human EXOC5 (exocyst complex component 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| bicuspid aortic valve disease | exoc5uab3/uab3 | standard conditions | Fulmer et al., 2019 |
| bicuspid aortic valve disease | exoc5sa23168/sa23168 | standard conditions | Fulmer et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Exocyst complex component Sec10-like | Exocyst complex component Sec10-like, alpha-helical bundle | Exocyst complex component Sec10, N-terminal |
|---|---|---|---|---|
|
UniProtKB:B0BLY0
|
708 |
Interactions and Pathways
No data available
Plasmids
No data available