Park et al., 2019 - 3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish. Scientific Reports   9:1138 Full text @ Sci. Rep.
52 Genes / Markers
Marker Type Symbol Name
Gene acer2 alkaline ceramidase 2
Gene asah1a N-acylsphingosine amidohydrolase (acid ceramidase) 1a
Gene asah1b N-acylsphingosine amidohydrolase (acid ceramidase) 1b
Gene asah2 N-acylsphingosine amidohydrolase 2
Gene atf4a activating transcription factor 4a
Gene atf6 activating transcription factor 6
Gene baxb BCL2 associated X, apoptosis regulator b
Gene bcl2l11 BCL2 like 11
Gene bida BH3 interacting domain death agonist
Gene col1a1a collagen, type I, alpha 1a
Gene cpt1aa carnitine palmitoyltransferase 1Aa (liver)
Gene ddit3 DNA-damage-inducible transcript 3
Gene dnajc3a DnaJ (Hsp40) homolog, subfamily C, member 3a
Gene dnm1l dynamin 1-like
Gene edem1 ER degradation enhancer, mannosidase alpha-like 1
Gene ern1 endoplasmic reticulum to nucleus signaling 1
Gene fasn fatty acid synthase
Gene gadd45aa growth arrest and DNA-damage-inducible, alpha, a
Gene gapdh glyceraldehyde-3-phosphate dehydrogenase
Gene gba1 glucosylceramidase beta 1
Gene gclc glutamate-cysteine ligase, catalytic subunit
Gene gpx1a glutathione peroxidase 1a
Gene gpx4a glutathione peroxidase 4a
Gene gsr glutathione reductase
Gene gss glutathione synthetase
Gene gstp1.1 glutathione S-transferase pi 1.1
Gene gstp1.2 glutathione S-transferase pi 1.2
Gene hsp90b1 heat shock protein 90, beta (grp94), member 1
Gene hspa5 heat shock protein 5
Gene il1b interleukin 1, beta
Gene kdsr 3-ketodihydrosphingosine reductase
Gene lpla lipoprotein lipase a
Gene mfn1b mitofusin 1b
Gene mt-nd1 NADH dehydrogenase 1, mitochondrial
Gene nfe2l2a nfe2 like bZIP transcription factor 2a
Gene nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Gene opa1 OPA1 mitochondrial dynamin like GTPase
Gene ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Gene prdx4 peroxiredoxin 4
Gene serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene sgpl1 sphingosine-1-phosphate lyase 1
Gene sgpp1b sphingosine-1-phosphate phosphatase 1b
Gene smpd1 sphingomyelin phosphodiesterase 1
Gene sod2 superoxide dismutase 2, mitochondrial
Gene sphk1 sphingosine kinase 1
Gene sphk2 sphingosine kinase 2
Gene srebf1 sterol regulatory element binding transcription factor 1
Gene srebf2 sterol regulatory element binding transcription factor 2
Gene tnfa tumor necrosis factor a (TNF superfamily, member 2)
Gene txnl1 thioredoxin-like 1
Gene txnl4a thioredoxin-like 4A
Gene xbp1 X-box binding protein 1