CRISPR

CRISPR1-lpla

ID

ZDB-CRISPR-170913-1

Name

CRISPR1-lpla

Previous Names

CRISPR1-lpl

Target

lpla (1)

Sequence

5' - GGCTGAAATTGATTATCCTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sd51	lpla

Expression

Gene expression in Wild Types + CRISPR1-lpla

No data available

Phenotype

Phenotype resulting from CRISPR1-lpla

No data available

Phenotype of all Fish created by or utilizing CRISPR1-lpla

Phenotype	Fish	Conditions	Figures
thymus rag1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 3 from Liu et al., 2018
hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 3 from Liu et al., 2018
caudal hematopoietic tissue hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	chemical treatment by injection: very-low-density lipoprotein	Fig. 4 from Liu et al., 2018
blood cell decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 2 from Liu et al., 2018
whole organism apoc2 expression increased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 2 from Liu et al., 2018
whole organism lipid increased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. S3 from Liu et al., 2018
caudal hematopoietic tissue hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	chemical treatment by injection: very-low-density lipoprotein	Fig. 4 from Liu et al., 2018
blood plasma triglyceride increased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 2 from Liu et al., 2018
whole organism hemoglobin decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 2 from Liu et al., 2018
thymus lymphocyte rag1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 3 from Liu et al., 2018
caudal hematopoietic tissue hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 4 from Liu et al., 2018
caudal hematopoietic tissue hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 4 from Liu et al., 2018
erythroblast hbbe1.1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 3 from Liu et al., 2018
caudal vein blood cell decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 2 from Liu et al., 2018
caudal hematopoietic tissue erythroblast hbbe1.1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	chemical treatment by injection: very-low-density lipoprotein	Fig. 4 from Liu et al., 2018
hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 3 from Liu et al., 2018
caudal hematopoietic tissue erythroblast hbbe1.1 expression decreased amount, abnormal	lpla^sd51/sd51 (AB)	control	Fig. 4 from Liu et al., 2018

Citations