CRISPR

CRISPR1-hif1aa

ID
ZDB-CRISPR-171002-7
Name
CRISPR1-hif1aa
Previous Names
None
Target
Sequence
5' - AGCCTCAATGTTCGCCGGAT - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
bns89 hif1aa
Expression
Gene expression in Wild Types + CRISPR1-hif1aa
No data available
Phenotype
Phenotype resulting from CRISPR1-hif1aa
No data available
Phenotype of all Fish created by or utilizing CRISPR1-hif1aa
Phenotype Fish Conditions Figures
respiratory gaseous exchange by respiratory system increased frequency, abnormal hif1aabns89/bns89 hypoxia Fig. 1 from Mandic et al., 2018
whole organism hif1aa expression decreased amount, abnormal hif1aabns89/bns89 standard conditions Fig. 1 with image from Gerri et al., 2017
respiratory gaseous exchange by respiratory system frequency, abnormal hif1aabns89/bns89 hypoxia Fig. 2Fig. 6 from Mandic et al., 2018
response to hypoxia process quality, abnormal hif1aabns89/bns89 hypoxia Fig. 1Fig. 2Fig. 6 from Mandic et al., 2018
whole organism myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 4 from Gerri et al., 2018
blood vessel endothelial cell cell population proliferation decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89 cryoablation: heart Fig. 3 with image from Marín-Juez et al., 2019
trunk has fewer parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 3 with image from Gerri et al., 2017
ventral wall of dorsal aorta macrophage migration decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 3 with image from Gerri et al., 2017
trunk has fewer parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 3 with image from Gerri et al., 2017
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 1Fig. 4 from Gerri et al., 2018
whole organism gata2b expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 5 from Gerri et al., 2018
ventral wall of dorsal aorta myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 1Fig. 4 from Gerri et al., 2018
whole organism runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 4 from Gerri et al., 2018
whole organism hif1aa expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 2 with image from Gerri et al., 2017
regenerating tissue cardiac ventricle cxcl12b expression amount, ameliorated hif1abbns90/bns90; hif1aabns89/bns89 cryoablation: heart Fig. 3 with image from Marín-Juez et al., 2019
trunk has fewer parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 chemical treatment by environment: dimethyloxalylglycine Fig. 3 with image from Gerri et al., 2017
ventral wall of dorsal aorta anatomical region has extra parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 3 with image from Gerri et al., 2017
respiratory gaseous exchange by respiratory system increased frequency, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 5 from Mandic et al., 2018
ventral wall of dorsal aorta anatomical region has extra parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 3 with image from Gerri et al., 2017
whole organism notch1b expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 5 from Gerri et al., 2018
ventral wall of dorsal aorta macrophage migration decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89 chemical treatment by environment: dimethyloxalylglycine Fig. 3 with image from Gerri et al., 2017
ventral wall of dorsal aorta anatomical region has extra parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89 chemical treatment by environment: dimethyloxalylglycine Fig. 3 with image from Gerri et al., 2017
ventral wall of dorsal aorta runx1 expression amount, ameliorated hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 4 from Gerri et al., 2018
regenerating tissue cell population proliferation decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89 cryoablation: heart Fig. 3 with image from Marín-Juez et al., 2019
respiratory gaseous exchange by respiratory system increased frequency, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 1 from Mandic et al., 2018
whole organism notch1a expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 control Fig. 5 from Gerri et al., 2018
ventral wall of dorsal aorta macrophage migration decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 3 with image from Gerri et al., 2017
hematopoietic system runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 1 from Gerri et al., 2018
respiratory gaseous exchange by respiratory system frequency, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 1Fig. 2Fig. 6 from Mandic et al., 2018
hematopoietic system myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 1 from Gerri et al., 2018
ventral wall of dorsal aorta myb expression amount, ameliorated hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 4 from Gerri et al., 2018
whole organism hif1ab expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 standard conditions Fig. 2 with image from Gerri et al., 2017
response to hypoxia process quality, abnormal hif1abbns90/bns90; hif1aabns89/bns89 hypoxia Fig. 1Fig. 2Fig. 6 from Mandic et al., 2018
dorsal longitudinal anastomotic vessel absent, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg control Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel absent, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel absent, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel malformed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
intersegmental vessel broken, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
intersegmental vessel detached from dorsal longitudinal anastomotic vessel, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development process quality, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg control Fig. 2 with image from Gerri et al., 2017
intersegmental vessel closed, exacerbated hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
intersegmental vessel closed, exacerbated hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development process quality, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
intersegmental vessel detached from dorsal longitudinal anastomotic vessel, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development process quality, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
intersegmental vessel closed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg control Fig. 2 with image from Gerri et al., 2017
intersegmental vessel broken, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg hypoxia Fig. 2 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel malformed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg chemical treatment by environment: dimethyloxalylglycine Fig. 2 with image from Gerri et al., 2017
macrophage mCherry expression absent, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 6 with image from Gerri et al., 2017
ventral wall of dorsal aorta macrophage migration decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 3 with image from Gerri et al., 2017
trunk has fewer parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 3 with image from Gerri et al., 2017
intersegmental vessel regeneration decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg chemical treatment by environment: dimethyloxalylglycine Fig. 7 with image from Gerri et al., 2017
ventral wall of dorsal aorta anatomical region has extra parts of type macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 3 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel malformed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 6 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel angiogenic sprout dissociated from macrophage, abnormal hif1abbns90/bns90; hif1aabns89/bns89; s843Tg; ump2Tg standard conditions Fig. 6 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg chemical ablation: macrophage, chemical treatment by environment: metronidazole Fig. 4 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development decreased occurrence, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg control Fig. 4 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel malformed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg chemical ablation: macrophage, chemical treatment by environment: metronidazole Fig. 4 with image from Gerri et al., 2017
dorsal longitudinal anastomotic vessel malformed, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg control Fig. 4 with image from Gerri et al., 2017
intersegmental vessel broken, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg chemical ablation: macrophage, chemical treatment by environment: metronidazole Fig. 4 with image from Gerri et al., 2017
intersegmental vessel broken, abnormal hif1abbns90/bns90; hif1aabns89/bns89; c264Tg; gl24Tg; s843Tg control Fig. 4 with image from Gerri et al., 2017
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b hypoxia Fig. 4 from Gerri et al., 2018
ventral wall of dorsal aorta myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b control Fig. 4 from Gerri et al., 2018
ventral wall of dorsal aorta myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b hypoxia Fig. 4 from Gerri et al., 2018
whole organism myb expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b standard conditions Fig. 4 from Gerri et al., 2018
whole organism runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b standard conditions Fig. 4 from Gerri et al., 2018
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal hif1abbns90/bns90; hif1aabns89/bns89 + MO1-epas1a + MO3-epas1b control Fig. 4 from Gerri et al., 2018
Citations