Martin et al., 2014 - Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nature Genetics   46:1283-92 Full text @ Nat. Genet.
Human Disease / Model Data (2 Records)
Human Disease Fish Environment Evidence Code
ciliopathy AB/TU + MO2-plk4 + MO3-plk4 standard conditions
Seckel syndrome
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