Blackburn et al., 2014 - Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation. Cancer Cell   25:366-78 Full text @ Cancer Cell
30 Genes / Markers
Marker Type Symbol Name
Gene akt2 v-akt murine thymoma viral oncogene homolog 2
Gene akt3a v-akt murine thymoma viral oncogene homolog 3a
Gene cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Gene cd4-1 CD4-1 molecule
Gene cd8a CD8a molecule
Gene cdc25b cell division cycle 25B
Gene eef1a1l2 eukaryotic translation elongation factor 1 alpha 1, like 2
Gene fbxw7 F-box and WD repeat domain containing 7
Gene her6 hairy-related 6
Gene hrasa HRas proto-oncogene, GTPase a
Gene il7r interleukin 7 receptor
Gene kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene lck LCK proto-oncogene, Src family tyrosine kinase
Gene lmo2 LIM domain only 2 (rhombotin-like 1)
Gene mdm2 MDM2 proto-oncogene
Gene myca MYC proto-oncogene, bHLH transcription factor a
Gene mycb MYC proto-oncogene, bHLH transcription factor b
Gene notch1a notch receptor 1a
Gene notch1b notch receptor 1b
Gene nras NRAS proto-oncogene, GTPase
Gene odc1 ornithine decarboxylase 1
Gene pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Gene pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene ptena phosphatase and tensin homolog A
Gene ptenb phosphatase and tensin homolog B
Gene ptpn11a protein tyrosine phosphatase non-receptor type 11a
Gene rhebl1 Ras homolog, mTORC1 binding like 1
Gene tal1 T-cell acute lymphocytic leukemia 1
Gene tp53 tumor protein p53
Gene trac T cell receptor alpha constant