Gene
vps37a
- ID
- ZDB-GENE-030131-8312
- Name
- VPS37A subunit of ESCRT-I
- Symbol
- vps37a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Involved in locomotory behavior. Predicted to localize to ESCRT I complex and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zivony-Elboum et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 53 | Alliance | Spastic paraplegia 53, autosomal recessive | 614898 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ESCRT assembly domain | Helix hairpin bin domain superfamily | Modifier of rudimentary, Modr | Ubiquitin-conjugating enzyme/RWD-like |
|---|---|---|---|---|---|
|
UniProtKB:Q6TH08
|
387 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
vps37a-201
(1)
|
Havana | 2002 nt | |
| mRNA |
vps37a-202
(1)
|
Havana | 443 nt |
Interactions and Pathways
No data available
Plasmids
No data available