Gene
nsmfb
- ID
- ZDB-GENE-080603-4
- Name
- NMDA receptor synaptonuclear signaling and neuronal migration factor b
- Symbol
- nsmfb Nomenclature History
- Previous Names
-
- nelf
- nelfb
- si:ch73-239f21.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Involved in positive regulation of axon extension and positive regulation of neuron migration. Predicted to localize to several cellular components, including dendrite; nucleus; and postsynaptic density. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia and hypogonadotropic hypogonadism 9 with or without anosmia. Is expressed in brain and olfactory epithelium. Orthologous to human NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Palevitch et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 9 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 9 with or without anosmia | 614838 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR033374 | NMDA receptor synaptonuclear signalling and neuronal migration factor |
Domain Details Per Protein
| Protein | Length | NMDA receptor synaptonuclear signalling and neuronal migration factor |
|---|---|---|
|
UniProtKB:A0A8M9Q3Q1
|
579 | |
|
UniProtKB:A0A0R4INI9
|
568 | |
|
UniProtKB:A0A8M9PY12
|
593 | |
|
UniProtKB:B8PYG1
|
570 | |
|
UniProtKB:A0A8M9Q8Z5
|
560 |
Interactions and Pathways
No data available
Plasmids
No data available