Gene

odc1

ID

ZDB-GENE-010816-1

Name

ornithine decarboxylase 1

Symbol

odc1 Nomenclature History

Previous Names

odc
CHUNP6922
fc54f04
fi06d08
ornithine decarboxylase
wu:fc54f04 (1)
wu:fi06d08 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have ornithine decarboxylase activity. Involved in eye photoreceptor cell development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Is expressed in neuromast and ovary. Orthologous to several human genes including ODC1 (ornithine decarboxylase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

18 figures from 17 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55204 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With odc1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Bachmann-Bupp syndrome	619075

Associated With odc1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR022653	Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
Conserved_site	IPR022657	Orn/DAP/Arg decarboxylase 2, conserved site
Domain	IPR022643	Orn/DAP/Arg decarboxylase 2, C-terminal
Domain	IPR022644	Orn/DAP/Arg decarboxylase 2, N-terminal
Family	IPR000183	Ornithine/DAP/Arg decarboxylase
Family	IPR002433	Ornithine decarboxylase
Homologous_superfamily	IPR009006	Alanine racemase/group IV decarboxylase, C-terminal
Homologous_superfamily	IPR029066	PLP-binding barrel

Domain Details Per Protein

Protein	Length	Alanine racemase/group IV decarboxylase, C-terminal	Orn/DAP/Arg decarboxylase 2, conserved site	Orn/DAP/Arg decarboxylase 2, C-terminal	Orn/DAP/Arg decarboxylase 2, N-terminal	Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site	Ornithine/DAP/Arg decarboxylase	Ornithine decarboxylase	PLP-binding barrel
UniProtKB:Q9DGJ4 InterPro	461

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	odc1-201 (1) Ensembl	Havana	545 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	odc1-202 (1) Ensembl	Havana	2140 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	odc1-203 (1) Ensembl	Havana	734 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-odc1	monoclonal	odc1	IgG2b	Mouse	WB	Sigma-Aldrich	3

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations