Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
ZFIN ID:
ZDB-PERS-960805-509
Sepich, Diane
Email:
sepichd@wustl.edu
URL:
Affiliation:
Lila Solnica-Krezel lab
Address:
Department of Developmental Biology Washington University School of Medicine 4566 Scott Avenue St. Louis, MO 63110 USA
Country:
United States
Phone:
(314) 362-9398
Fax:
(314) 362-7058
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Stark, B.C., Gao, Y., Sepich, D.S., Belk, L., Culver, M.A., Hu, B., Mekel, M., Ferris, W., Shin, J., Solnica-Krezel, L., Lin, F., Cooper, J.A. (2021) CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish. Developmental Biology. 481:148-159
Gray, R.S., Gonzalez, R., Ackerman, S.D., Minowa, R., Griest, J.F., Bayrak, M.N., Troutwine, B., Canter, S., Monk, K.R., Sepich, D.S., Solnica-Krezel, L. (2020) Postembryonic screen for mutations affecting spine development in zebrafish. Developmental Biology. 471:18-33
Whittle, J., Antunes, L., Harris, M., Upshaw, Z., Sepich, D.S., Johnson, A.N., Mokalled, M., Solnica-Krezel, L., Dobbs, M.B., Gurnett, C.A. (2020) MYH3-associated distal arthrogryposis zebrafish model is normalized with para-aminoblebbistatin. EMBO Molecular Medicine. 12(11):e12356
Troutwine, B.R., Gontarz, P., Konjikusic, M.J., Minowa, R., Monstad-Rios, A., Sepich, D.S., Kwon, R.Y., Solnica-Krezel, L., Gray, R.S. (2020) The Reissner Fiber Is Highly Dynamic In Vivo and Controls Morphogenesis of the Spine. Current biology : CB. 30(12):2353-2362.e3
Budine, T.E., de Sena-Tomás, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Kreze, L. (2020) Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development. Developmental Biology. 462(2):223-234
Liu, Y., Sepich, D.S., Solnica-Krezel, L. (2017) Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genetics. 13:e1006564
Xie, H., Ye, D., Sepich, D., Lin, F. (2016) S1pr2/Gα13 signaling regulates the migration of endocardial precursors by controlling endoderm convergence. Developmental Biology. 414:228-43
Sepich, D.S., Solnica-Krezel, L. (2016) Intracellular Golgi Complex Organization Reveals Tissue Specific Polarity during Zebrafish Embryogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 245(6):678-91
Li, X., Roszko, I., Sepich, D.S., Ni, M., Hamm, H.E., Marlow, F.L., and Solnica-Krezel, L. (2013) Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development (Cambridge, England). 140(14):3028-3039
Carlin, D., Sepich, D., Grover, V.K., Cooper, M.K., Solnica-Krezel, L., and Inbal, A. (2012) Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling. Development (Cambridge, England). 139(14):2614-2624
Schepis, A., Sepich, D., and Nelson, W.J. (2012) αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly. Development (Cambridge, England). 139(3):537-46
Wu, S.Y., Shin, J., Sepich, D.S., and Solnica-Krezel, L. (2012) Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation. PLoS Biology. 10(10):e1001403
Sepich, D.S., Usmani, M., Pawlicki, S., and Solnica-Krezel, L. (2011) Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development (Cambridge, England). 138(3):543-552
Speirs, C.K., Jernigan, K.K., Kim, S.H., Cha, Y.I., Lin, F., Sepich, D.S., DuBois, R.N., Lee, E., and Solnica-Krezel, L. (2010) Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development (Cambridge, England). 137(8):1327-1337
Calmelet, C., and Sepich, D. (2010) Surface tension and modeling of cellular intercalation during zebrafish gastrulation. Mathematical biosciences and engineering : MBE. 7(2):259-275
Lin, F., Chen, S., Sepich, D.S., Panizzi, J.R., Clendenon, S.G., Marrs, J.A., Hamm, H.E., and Solnica-Krezel, L. (2009) Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton. The Journal of cell biology. 184(6):909-921
Zeng, X.X., Wilm, T.P., Sepich, D.S., and Solnica-Krezel, L. (2007) Apelin and Its Receptor Control Heart Field Formation during Zebrafish Gastrulation. Developmental Cell. 12(3):391-402
Cha, Y.I., Kim, S.H., Sepich, D., Buchanan, F.G., Solnica-Krezel, L., and Dubois, R.N. (2006) Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes & Development. 20(1):77-86
Sepich, D.S., Calmelet, C., Kiskowski, M., and Solnica-Krezel, L. (2005) Initiation of convergence and extension movements of lateral mesoderm during zebrafish gastrulation. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(2):279-292
Lin, F., Sepich, D.S., Chen, S., Topczewski, J., Yin, C., Solnica-Krezel, L., and Hamm, H. (2005) Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. The Journal of cell biology. 169(5):777-787
Sepich, D.S., and Solnica-Krezel, L. (2005) Analysis of cell movements in zebrafish embryos: morphometrics and measuring movement of labeled cell populations in vivo. Methods in molecular biology (Clifton, N.J.). 294:211-234
Myers, D., Sepich, D. and Solnica-Krezel, L. (2002) Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?. Trends in genetics : TIG. 18(9):447-455
Jessen, J.R., Topczewski, J., Bingham, S., Sepich, D.S., Marlow, F., Chandrasekhar, A., and Solnica-Krezel, L. (2002) Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nature cell biology. 4(8):610-615
Solnica-Krezel, L., Marlow, F., Topczewski, J., Jessen, J., and Sepich, D. (2002) Regulation of cell polarity during zebrafish gastrulation. Developmental Biology. 247(2):479
Marlow, F., Topczewski, J., Sepich, D., and Solnica-Krezel, L. (2002) Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements. Current biology : CB. 12(11):876-884
Myers, D., Sepich, D., and Solnica-Krezel, L. (2002) Bmp activity gradient regulates convergent extension during zebrafish gastrulation. Developmental Biology. 243(1):81-98
Topczewski, J., Sepich, D.S., Myers, D.C., Walker, C., Amores, A., Lele, Z., Hammerschmidt, M., Postlethwait, J., and Solnica-Krezel, L. (2001) The zebrafish glypican Knypek controls cell polarity during gastrulation movements of convergent extension. Developmental Cell. 1(2):251-264
Solnica-Krezel, L., Topczewski, J., Sepich, D., Myers, D., Marlow, F., and Jessen, J. (2001) Genetic control of convergent extension movements during zebrafish gastrulation. Developmental Biology. 235(1):175 (#17)
Henry, C.A., Crawford, B.D., Sepich, D., Cooper, M.S., and Hille, M. (2000) Subcellular localization of focal adhesion kinase during zebrafish organogenesis: Distinct roles for FAK in notochord and somite morphogenesis. Molecular biology of the cell. 11:297
Sepich, D.S., Myers, D.C., Short, R., Topczewski, J., Marlow, F., and Solnica-Krezel, L. (2000) Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis (New York, N.Y. : 2000). 27(4):159-173
Sepich, D.S., Wegner, J., O'Shea, S., and Westerfield, M. (1998) An altered intron inhibits synthesis of the acetylcholine receptor alpha-subunit in the paralyzed zebrafish mutant nic1. Genetics. 184:361-372
Sepich, D.S., Ho, R.K., and Westerfield, M. (1994) Autonomous expression of the nic1 acetylcholine receptor mutation in zebrafish muscle cells. Developmental Biology. 161:84-90
Sepich, D.S. (1994) Characterizations of the zebrafish acetylcholine receptor mutant, nic1. Ph.D. Thesis.
Kimmel, C.B., Sepich, D.S., and Trevarrow, B. (1988) Development of segmentation in zebrafish. Development (Cambridge, England). 104:197-208
NON-ZEBRAFISH PUBLICATIONS
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.