ZFIN Person: Vejnar, Charles

ZFIN ID: ZDB-PERS-160909-9

Vejnar, Charles

Email:	charles.vejnar@yale.edu
URL:
Affiliation:	Giraldez Lab
Address:	Yale University School of Medicine 333 Cedar Street SHMI room 142 New Haven CT USA
Country:	United States
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Pownall, M.E., Miao, L., Vejnar, C.E., M'Saad, O., Sherrard, A., Frederick, M.A., Benitez, M.D.J., Boswell, C.W., Zaret, K.S., Bewersdorf, J., Giraldez, A.J. (2023) Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin. Science (New York, N.Y.). 381:9210092-100

Tornini, V.A., Miao, L., Lee, H.J., Gerson, T., Dube, S.E., Schmidt, V., Kroll, F., Tang, Y., Du, K., Kuchroo, M., Vejnar, C.E., Bazzini, A.A., Krishnaswamy, S., Rihel, J., Giraldez, A.J. (2023) linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells. eLIFE. 12:

Bogoch, Y., Jamieson-Lucy, A., Vejnar, C.E., Levy, K., Giraldez, A.J., Mullins, M.C., Elkouby, Y.M. (2022) Stage Specific Transcriptomic Analysis and Database for Zebrafish Oogenesis. Frontiers in cell and developmental biology. 10:826892

Vicencio, J., Sánchez-Bolaños, C., Moreno-Sánchez, I., Brena, D., Vejnar, C.E., Kukhtar, D., Ruiz-López, M., Cots-Ponjoan, M., Rubio, A., Melero, N.R., Crespo-Cuadrado, J., Carolis, C., Pérez-Pulido, A.J., Giráldez, A.J., Kleinstiver, B.P., Cerón, J., Moreno-Mateos, M.A. (2022) Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes. Nature communications. 13:2601

Miao, L., Tang, Y., Bonneau, A.R., Chan, S.H., Kojima, M.L., Pownall, M.E., Vejnar, C.E., Gao, F., Krishnaswamy, S., Hendry, C.E., Giraldez, A.J. (2022) The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation. Molecular Cell. 82(5):986-1002.e9

Jamieson-Lucy, A.H., Kobayashi, M., James Aykit, Y., Elkouby, Y., Escobar-Aguirre, M., Vejnar, C., Giraldez, A., Mullins, M.C. (2022) A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb. Developmental Biology. 484:1-11

Maerker, M., Getwan, M., Dowdle, M.E., McSheene, J.C., Gonzalez, V., Pelliccia, J.L., Hamilton, D.S., Yartseva, V., Vejnar, C., Tingler, M., Minegishi, K., Vick, P., Giraldez, A.J., Hamada, H., Burdine, R.D., Sheets, M.D., Blum, M., Schweickert, A. (2021) Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nature communications. 12:5482

Vejnar, C.E., Abdelmessih, M., Takacs, C., Yartseva, V., Oikonomou, P., Christiano, R., Stoeckius, M., Lau, S., Lee, M., Beaudoin, J.D., Musaev, D., Darwich-Codore, H., Walther, T., Tavazoie, S., Cifuentes, D., Giraldez, A. (2019) Genome wide analysis of 3'-UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Genome research. 29(7):1100-1114

Chan, S.H., Tang, Y., Miao, L., Darwich-Codore, H., Vejnar, C.E., Beaudoin, J.D., Musaev, D., Fernandez, J.P., Benitez, M.D.J., Bazzini, A.A., Moreno-Mateos, M.A., Giraldez, A.J. (2019) Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Developmental Cell. 49:867-881.e8

Beaudoin, J.D., Novoa, E.M., Vejnar, C.E., Yartseva, V., Takacs, C.M., Kellis, M., Giraldez, A.J. (2018) Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Nature structural & molecular biology. 25(8):677-686

Fernandez, J.P., Vejnar, C.E., Giraldez, A.J., Rouet, R., Moreno-Mateos, M.A. (2018) Optimized CRISPR-Cpf1 system for genome editing in zebrafish. Methods (San Diego, Calif.). 150:11-18

Moreno-Mateos, M.A., Fernandez, J.P., Rouet, R., Vejnar, C.E., Lane, M.A., Mis, E., Khokha, M.K., Doudna, J.A., Giraldez, A.J. (2017) CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing. Nature communications. 8:2024

Kasper, D.M., Moro, A., Ristori, E., Narayanan, A., Hill-Teran, G., Fleming, E., Moreno-Mateos, M., Vejnar, C.E., Zhang, J., Lee, D., Gu, M., Gerstein, M., Giraldez, A., Nicoli, S. (2017) MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Developmental Cell. 40:552-565.e5

Yartseva, V., Takacs, C.M., Vejnar, C.E., Lee, M.T., Giraldez, A.J. (2017) RESA identifies mRNA-regulatory sequences at high resolution. Nature Methods. 14(2):201-207

Bazzini, A.A., Del Viso, F., Moreno-Mateos, M.A., Johnstone, T.G., Vejnar, C.E., Qin, Y., Yao, J., Khokha, M.K., Giraldez, A.J. (2016) Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition. The EMBO journal. 35(19):2087-2103

Moreno-Mateos, M.A., Vejnar, C.E., Beaudoin, J.D., Fernandez, J.P., Mis, E.K., Khokha, M.K., Giraldez, A.J. (2015) CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nature Methods. 12:982-8

NON-ZEBRAFISH PUBLICATIONS