ZFIN Person: Karchner, Sibel

ZFIN ID: ZDB-PERS-160509-1

Karchner, Sibel

Email:	skarchner@whoi.edu
URL:
Affiliation:	Hahn Lab
Address:	Biology Department Woods Hole Oceanographic Institution MS-32 Woods Hole, MA 02543
Country:	United States
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

James, B.D., Karchner, S.I., Walsh, A.N., Aluru, N., Franks, D.G., Sullivan, K.R., Reddy, C.M., Ward, C.P., Hahn, M.E. (2023) Formulation Controls the Potential Neuromuscular Toxicity of Polyethylene Photoproducts in Developing Zebrafish. Environmental science & technology. 57(21):7966-7977

Aluru, N., Karchner, S.I. (2020) PCB126 exposure revealed alterations in m6A RNA modifications in transcripts associated with AHR activation. Toxicological sciences : an official journal of the Society of Toxicology. 179(1):84-94

Aluru, N., Krick, K.S., McDonald, A.M., Karchner, S.I. (2019) Developmental exposure to PCB153 (2,2',4,4',5,5'-hexachlorobiphenyl) alters circadian rhythms and the expression of clock and metabolic genes. Toxicological sciences : an official journal of the Society of Toxicology. 173(1):41-52

Ulin, A., Henderson, J., Pham, M.T., Meyo, J., Chen, Y., Karchner, S.I., Goldstone, J.V., Hahn, M.E., Williams, L.M. (2018) Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in zebrafish (Danio rerio). Toxicological sciences : an official journal of the Society of Toxicology. 167(2):536-545

Aluru, N., Karchner, S.I., Krick, K.S., Zhu, W., Liu, J. (2018) Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126).. Environmental Epigenetics. 4:dvy005

Holland, E.B., Goldstone, J.V., Pessah, I.N., Whitehead, A., Reid, N.M., Karchner, S.I., Hahn, M.E., Nacci, D.E., Clark, B.W., Stegeman, J.J. (2017) Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison. Aquatic toxicology (Amsterdam, Netherlands). 192:105-115

Aluru, N., Karchner, S.I., Glazer, L. (2017) Early life exposure to low levels of AHR agonist PCB126 (3,3',4,4',5-pentachlorobiphenyl) reprograms gene expression in adult brain. Toxicological sciences : an official journal of the Society of Toxicology. 160(2):386-397

Hahn, M.E., Timme-Laragy, A.R., Karchner, S.I., Stegeman, J.J. (2015) Nrf2 and Nrf2-related proteins in development and developmental toxicity:Insights from studies in zebrafish (danio rerio). Free radical biology & medicine. 88(Pt B):275-89

Hahn, M.E., McArthur, A.G., Karchner, S.I., Franks, D.G., Jenny, M.J., Timme-Laragy, A.R., Stegeman, J.J., Woodin, B.R., Cipriano, M.J., Linney, E. (2014) The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. PLoS One. 9:e113158

Bainy, A.C., Kubota, A., Goldstone, J.V., Lille-Langøy, R., Karchner, S.I., Celander, M.C., Hahn, M.E., Goksøyr, A., and Stegeman, J.J. (2013) Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 142-143:447-457

Amemiya, C.T., Alfoldi, J., Lee, A.P., Fan, S., Philippe, H., MacCallum, I., Braasch, I., Manousaki, T., Schneider, I., Rohner, N., Organ, C., Chalopin, D., Smith, J.J., Robinson, M., Dorrington, R.A., Gerdol, M., Aken, B., Biscotti, M.A., Barucca, M., Baurain, D., Berlin, A.M., Blatch, G.L., Buonocore, F., Burmester, T., Campbell, M.S., Canapa, A., Cannon, J.P., Christoffels, A., de Moro, G., Edkins, A.L., Fan, L., Fausto, A.M., Feiner, N., Forconi, M., Gamieldien, J., Gnerre, S., Gnirke, A., Goldstone, J.V., Haerty, W., Hahn, M.E., Hesse, U., Hoffmann, S., Johnson, J., Karchner, S.I., Karaku, S., Lara, M., Levin, J.Z., Litman, G.W., Mauceli, E., Miyake, T., Mueller, M.G., Nelson, D.R., Nitsche, A., Olmo, E., Ota, T., Pallavicini, A., Panji, S., Picone, B., Ponting, C.P., Prohaska, S.J., Przybylski, D., Saha, N.R., Ravi, V., Ribeiro, F.J., Sauka-Spengler, T., Scapigliati, G., Searle, S.M.J., Sharpe, T., Simakov, O., Stadler, P.F., Stegeman, J.J., Sumiyama, K., Tabbaa, D., Tafer, H., Turner-Maier, J., van Heusden, P., White, S., Williams, L., Yandell, M., Brinkmann, H., Volff, J.N., Tabin, C.J., Shubin, N., Schartl, M., Jaffe, D.B., Postlethwait, J.H., Venkatesh, B., Palma, F.D., Lander, E.S., Meyer, A., and Lindblad-Toh, K. (2013) The African coelacanth genome provides insights into tetrapod evolution. Nature. 496:311-316

Timme-Laragy, A.R., Karchner, S.I., Franks, D.G., Jenny, M.J., Harbeitner, R.C., Goldstone, J.V., McArthur, A.G., and Hahn, M.E. (2012) Nrf2b: novel zebrafish paralog of the oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2). The Journal of biological chemistry. 287(7):4609-4627

Jenny, M.J., Karchner, S., Franks, D., Woodin, B.W., Stegeman, J.J., and Hahn, M.E. (2009) Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin). Toxicological sciences : an official journal of the Society of Toxicology. 110(2):426-441

NON-ZEBRAFISH PUBLICATIONS