ZFIN Person: Keatinge, Marcus

ZFIN ID: ZDB-PERS-140513-4

Keatinge, Marcus

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Affiliation:	Bandmann Lab
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Country:	UK
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Keatinge, M., Gegg, M.E., Watson, L., Mortiboys, H., Li, N., Dunning, M., Ailani, D., Bui, H., van Rens, A., Lefeber, D.J., Schapira, A.H.V., MacDonald, R.B., Bandmann, O. (2023) Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency. Disease models & mechanisms. 16(6):

Leggieri, A., García-González, J., Torres-Perez, J.V., Havelange, W., Hosseinian, S., Mech, A.M., Keatinge, M., Busch-Nentwich, E.M., Brennan, C.H. (2022) Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish. Frontiers in neuroscience. 16:794653

Larbalestier, H., Keatinge, M., Watson, L., White, E., Gowda, S., Wei, W., Koler, K., Semenova, S.A., Elkin, A.M., Rimmer, N., Sweeney, S.T., Mazzolini, J., Sieger, D., Hide, W., McDearmid, J., Panula, P., MacDonald, R.B., Bandmann, O. (2021) GCH1 deficiency activates brain innate immune response and impairs tyrosine hydroxylase homeostasis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(4):702-716

Herzog, C., Greenald, D., Larraz, J., Keatinge, M., Herrgen, L. (2020) RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo. Biology Open. 9(5):

Soman, S.K., Bazała, M., Keatinge, M., Bandmann, O., Kuznicki, J. (2019) Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease. Biology Open. 8(10):

Chia, K., Keatinge, M., Mazzolini, J., Sieger, D. (2019) Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation. eLIFE. 8:

Herzog, C., Pons Garcia, L., Keatinge, M., Greenald, D., Moritz, C., Peri, F., Herrgen, L. (2019) Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo. Development (Cambridge, England). 146(9):

Watson, L., Keatinge, M., Gegg, M., Bai, Q., Sandulescu, C., Vardi, A., Futerman, A.H., Schapira, A.H.V., Burton, E.A., Bandmann, O. (2019) Ablation of the pro-inflammatory master regulator miR-155 does not mitigate neuroinflammation or neurodegeneration in a vertebrate model of Gaucher's disease. Neurobiology of disease. 127:563-569

Tsarouchas, T.M., Wehner, D., Cavone, L., Munir, T., Keatinge, M., Lambertus, M., Underhill, A., Barrett, T., Kassapis, E., Ogryzko, N., Feng, Y., van Ham, T.J., Becker, T., Becker, C.G. (2018) Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration. Nature communications. 9:4670

Soman, S., Keatinge, M., Moein, M., DaCosta, M., Mortiboys, H., Skupin, A., Sugunan, S., Bazala, M., Kuznicki, J., Bandmann, O. (2017) Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1^-/- zebrafish.. The European journal of neuroscience. 45(4):528-535

Keatinge, M., Bui, H., Menke, A., Chen, Y.C., Sokol, A.M., Bai, Q., Ellett, F., Da Costa, M., Burke, D., Gegg, M., Trollope, L., Payne, T., McTighe, A., Mortiboys, H., de Jager, S., Nuthhall, H., Kuo, M.S., Fleming, A., Schapira, A.H., Renshaw, S.A., Highley, J.R., Chacinska, A., Panula, P., Burton, E.A., O'Neill, M.J., Bandmann, O. (2015) Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Human molecular genetics. 24(23):6640-52

NON-ZEBRAFISH PUBLICATIONS