ZFIN ID: ZDB-LAB-970909-56
Driever Lab
PI/Director: Driever, Wolfgang
Contact Person: Driever, Wolfgang
Email: driever@biologie.uni-freiburg.de
URL: http://www.biologie.uni-freiburg.de/data/bio1/driever/index.htm
Address: Abteilung Entwicklungsbiologie Institut für Biologie 1 Universität Freiburg Hauptstrasse 1 D-79104 Freiburg GERMANY
Phone: 49-761-203-2587 or 49-761-203-2588
Fax: 49-761-203-2597
Line Designation: m

Show first 50 of 640 genomic features

Genetic analysis of pattern formation in the early zebrafish embryo. Dissection of organizer activities; patterning in the neural plate; role of vertical and planar signals in neural patterning; mechanisms for specification of neuronal cells in the early brain.

Filippi, Alida Post-Doc Lunde, Karen Post-Doc Duerr, Katrin Graduate Student
Jainok, Chamaiphorn Graduate Student Kastenhuber, Edda Graduate Student Lachnit, Martina Graduate Student
Ledderose, Julia Graduate Student Löhr, Heiko Graduate Student Mahler, Julia Graduate Student
Tay, Tuan Leng Graduate Student Erhardt, Simone Research Staff Ettl, Anne-Kathrin Research Staff
Seifert, Franziska Research Staff Götter, Sabine Fish Facility Staff Buderer, Andrea

Riessland, M., Kaczmarek, A., Schneider, S., Swoboda, K.J., Löhr, H., Bradler, C., Grysko, V., Dimitriadi, M., Hosseinibarkooie, S., Torres-Benito, L., Peters, M., Upadhyay, A., Biglari, N., Kröber, S., Hölker, I., Garbes, L., Gilissen, C., Hoischen, A., Nürnberg, G., Nürnberg, P., Walter, M., Rigo, F., Bennett, C.F., Kye, M.J., Hart, A.C., Hammerschmidt, M., Kloppenburg, P., Wirth, B. (2017) Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. American journal of human genetics. 100(2):297-315
Reinig, S., Driever, W., Arrenberg, A.B. (2017) The Descending Diencephalic Dopamine System Is Tuned to Sensory Stimuli. Current biology : CB.
Martinez, A.F., Abe, Y., Hong, S., Molyneux, K., Yarnell, D., Löhr, H., Driever, W., Acosta, M.T., Arcos-Burgos, M., Muenke, M. (2016) An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility. Biological psychiatry. 80(12):943-954
Knierim, E., Hirata, H., Wolf, N.I., Morales-Gonzalez, S., Schottmann, G., Tanaka, Y., Rudnik-Schöneborn, S., Orgeur, M., Zerres, K., Vogt, S., van Riesen, A., Gill, E., Seifert, F., Zwirner, A., Kirschner, J., Goebel, H.H., Hübner, C., Stricker, S., Meierhofer, D., Stenzel, W., Schuelke, M. (2016) Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. American journal of human genetics. 98(3):473-89
Zang, J., Keim, J., Kastenhuber, E., Gesemann, M., Neuhauss, S.C. (2015) Recoverin depletion accelerates cone photoresponse recovery. Open Biology. 5(8)
Hu, Z., Holzschuh, J., Driever, W. (2015) Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos. PLoS One. 10:e0134299
Koch, P., Löhr, H.B., Driever, W. (2014) A Mutation in cnot8, Component of the Ccr4-Not Complex Regulating Transcript Stability, Affects Expression Levels of Developmental Regulators and Reveals a Role of Fgf3 in Development of Caudal Hypothalamic Dopaminergic Neurons. PLoS One. 9:e113829
Manoli, M., Driever, W. (2014) nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Frontiers in Neuroanatomy. 8:145
Kubo, F., Hablitzel, B., Dal Maschio, M., Driever, W., Baier, H., Arrenberg, A.B. (2014) Functional architecture of an optic flow-responsive area that drives horizontal eye movements in zebrafish. Neuron. 81:1344-59
Kotkamp, K., Kur, E., Wendik, B., Polok, B.K., Ben-Dor, S., Onichtchouk, D., Driever, W. (2014) Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. PLoS One. 9:e92356
Filippi, A., Mueller, T., and Driever, W. (2013) Vglut2 and gad expression reveal distinct patterns of dual GABAergic versus glutamatergic cotransmitter phenotypes of dopaminergic and noradrenergic neurons in the zebrafish brain. The Journal of comparative neurology. 522(9):2019-37
Kotkamp, K., Mössner, R., Allen, A., Onichtchouk, D., and Driever, W. (2013) A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis. Developmental Biology. 385(2):433-47
Lippok, B., Song, S., and Driever, W. (2013) Pou5f1 protein expression and posttranslational modification during early zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists. 243(3):468-77
Fernandes, A.M., Beddows, E., Filippi, A., and Driever, W. (2013) Orthopedia Transcription Factor otpa and otpb Paralogous Genes Function during Dopaminergic and Neuroendocrine Cell Specification in Larval Zebrafish. PLoS One. 8(9):e75002
Leichsenring, M., Maes, J., Mössner, R., Driever, W., and Onichtchouk, D. (2013) Pou5f1 transcription factor controls zygotic gene activation in vertebrates. Science (New York, N.Y.). 341(6149):1005-1009
von Niederhäusern, V., Kastenhuber, E., Stäuble, A., Gesemann, M., and Neuhauss, S.C. (2013) Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 242(12):1427-41
Kastenhuber, E., Gesemann, M., Mickoleit, M., and Neuhauss, S.C. (2013) Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes. Developmental dynamics : an official publication of the American Association of Anatomists. 242(11):1236-49
Mikut, R., Dickmeis, T., Driever, W., Geurts, P., Hamprecht, F.A., Kausler, B.X., Ledesma-Carbayo, M.J., Marée, R., Mikula, K., Pantazis, P., Ronneberger, O., Santos, A., Stotzka, R., Strähle, U., and Peyriéras, N. (2013) Automated Processing of Zebrafish Imaging Data: A Survey. Zebrafish. 10(3):401-21
Bensch, R., Song, S., Ronneberger, O., and Driever, W. (2013) Non-directional radial intercalation dominates deep cell behavior during zebrafish epiboly. Biology Open. 2(8):845-854
Fernandes, A.M., Fero, K., Driever, W., and Burgess, H.A. (2013) Enlightening the brain: Linking deep brain photoreception with behavior and physiology. BioEssays : news and reviews in molecular, cellular and developmental biology. 35(9):775-9
Vannier, C., Mock, K., Brabletz, T., and Driever, W. (2013) Zeb1 regulates E-cadherin and Epcam expression to control cell behavior in early zebrafish development. The Journal of biological chemistry. 288(26):18643-59
Arrenberg, A.B., and Driever, W. (2013) Integrating anatomy and function for zebrafish circuit analysis. Frontiers in neural circuits. 7:74
Song, S., Eckerle, S., Onichtchouk, D., Marrs, J.A., Nitschke, R., and Driever, W. (2013) Pou5f1-dependent EGF expression controls e-cadherin endocytosis, cell adhesion, and zebrafish epiboly movements. Developmental Cell. 24(5):486-501
Bader, H.L., Lambert, E., Guiraud, A., Malbouyres, M., Driever, W., Koch, M., and Ruggiero, F.. (2013) Zebrafish collagen XIV is transiently expressed in epithelia and is required for proper function of certain basement membranes. The Journal of biological chemistry. 288(10):6777-6787
Liu, F., Pogoda, H.M., Pearson, C.A., Ohyama, K., Löhr, H., Hammerschmidt, M., and Placzek, M. (2013) Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development (Cambridge, England). 140(5):1111-1122
Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013) Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development (Cambridge, England). 140(1):93-106
Fernandes, A.M., Fero, K., Arrenberg, A.B., Bergeron, S.A., Driever, W., and Burgess, H.A. (2012) Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae. Current biology : CB. 22(21):2042-2047
Filippi, A., Jainok, C., and Driever, W. (2012) Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development. Developmental Biology. 369(1):133-149
Manoli, M., and Driever, W. (2012) Fluorescence-Activated Cell Sorting (FACS) of Fluorescently Tagged Cells from Zebrafish Larvae for RNA Isolation. Cold Spring Harbor protocols. 2012(8):pdb.prot069633
Ronneberger, O., Liu, K., Rath, M., Rueβ, D., Mueller, T., Skibbe, H., Drayer, B., Schmidt, T., Filippi, A., Nitschke, R., Brox, T., Burkhardt, H., Driever, W. (2012) ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains. Nature Methods. 9(7):735-742
Voz, M.L., Coppieters, W., Manfroid, I., Baudhuin, A., Von Berg, V., Charlier, C., Meyer, D., Driever, W., Martial, J.A., and Peers, B. (2012) Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing. PLoS One. 7(4):e34671
Temerinac-Ott, M., Ronneberger, O., Ochs, P., Driever, W., Brox, T., and Burkhardt, H. (2012) Multiview deblurring for 3-D images from light-sheet-based fluorescence microscopy. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society. 21(4):1863-1873
Belting, H.G., Wendik, B., Lunde, K., Leichsenring, M., Mössner, R., Driever, W., and Onichtchouk, D. (2011) Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression. Developmental Biology. 356(2):323-36
Schweitzer, J., Löhr, H., Filippi, A., and Driever, W. (2011) Dopaminergic and noradrenergic circuit development in zebrafish. Developmental Neurobiology. 72(3):256-268
Brockschmidt, A., Filippi, A., Charbel Issa, P., Nelles, M., Urbach, H., Eter, N., Driever, W., and Weber, R.G. (2011) Neurologic and ocular phenotype in Pitt-Hopkins syndrome and a zebrafish model. Human genetics. 130(5):645-55
Iwafuchi-Doi, M., Yoshida, Y., Onichtchouk, D., Leichsenring, M., Driever, W., Takemoto, T., Uchikawa, M., Kamachi, Y., and Kondoh, H. (2011) The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates. Developmental Biology. 352(2):354-366
Löhr, H., and Hammerschmidt, M. (2011) Zebrafish in endocrine systems: recent advances and implications for human disease. Annual review of physiology. 73:183-211
Tay, T.L., Ronneberger, O., Ryu, S., Nitschke, R., and Driever, W. (2011) Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nature communications. 2:171
Mahler, J., Filippi, A., and Driever, W. (2010) DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(49):16621-16635
Stewart, R.A., Lee, J.S., Lachnit, M., Look, A.T., Kanki, J.P., and Henion, P.D. (2010) Chapter 5 - Studying peripheral sympathetic nervous system development and neuroblastoma in zebrafish. Meth. Cell. Biol.. 100:127-152
Epting, D., Wendik, B., Bennewitz, K., Dietz, C.T., Driever, W., and Kroll, J. (2010) The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish. Circulation research. 107(1):45-55
Onichtchouk, D., Geier, F., Polok, B., Messerschmidt, D., Mössner, R., Wendik, B., Song, S., Taylor, V., Timmer, J., and Driever, W. (2010) Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. Molecular Systems Biology. 6:354
Filippi, A., Mahler, J., Schweitzer, J., and Driever, W. (2010) Expression of the paralogous tyrosine hydroxylase encoding genes th1 and th2 reveals the full complement of dopaminergic and noradrenergic neurons in zebrafish larval and juvenile brain. The Journal of comparative neurology. 518(4):423-438
Kastenhuber, E., Kratochwil, C.F., Ryu, S., Schweitzer, J., and Driever, W. (2010) Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish. The Journal of comparative neurology. 518(4):439-458
Tiso, N., Filippi, A., Benato, F., Negrisolo, E., Modena, N., Vaccari, E., Driever, W., and Argenton, F. (2009) Differential expression and regulation of olig genes in zebrafish. The Journal of comparative neurology. 515(3):378-396
Kastenhuber, E., Kern U., Bonkowsky, J.L., Chien, C.B., Driever, W., and Schweitzer, J. (2009) Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(28):8914-8926
Löhr, H., Ryu, S., and Driever, W. (2009) Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Development (Cambridge, England). 136(6):1007-1017
Bader, H.L., Keene, D.R., Charvet, B., Veit, G., Driever, W., Koch, M., and Ruggiero, F. (2009) Zebrafish collagen XII is present in embryonic connective tissue sheaths (fascia) and basement membranes. Matrix biology : journal of the International Society for Matrix Biology. 28(1):32-43
Emmenlauer, M., Ronneberger, O., Ponti, A., Schwarb, P., Griffa, A., Filippi, A., Nitschke, R., Driever, W., and Burkhardt, H. (2009) XuvTools: free, fast and reliable stitching of large 3D datasets. J. Micros.. 233(Pt 1):42-60
Kastenhuber, E. (2009) Mechanisms of dopaminergic neuron differentiation and axonogenesis in zebrafish. Ph.D. Thesis. :196p
Löhr, H.B. (2009) A genetic screen for mutations affecting development of catecholaminergic systems in zebrafish reveals a novel role for the transcription factors Arnt2 and Sim1. Ph.D. Thesis. :199p
Mahler, J. (2009) Control of neurogenesis and neuronal differentiation of dopaminergic neurons in zebrafish. Ph.D. Thesis. :130p
Schweitzer, J., and Driever, W. (2009) Development of the dopamine systems in zebrafish. Advances in experimental medicine and biology. 651:1-14
Meng, S., Ryu, S., Zhao, B., Zhang, D.Q., Driever, W., and McMahon, D.G. (2008) Targeting retinal dopaminergic neurons in tyrosine hydroxylase-driven green fluorescent protein transgenic zebrafish. Molecular Vision. 14:2475-2483
Webb, A.E., Driever, W., and Kimelman, D. (2008) psoriasis regulates epidermal development in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 237(4):1153-1164
Isken, A., Golczak, M., Oberhauser, V., Hunzelmann, S., Driever, W., Imanishi, Y., Palczewski, K., and von Lintig, J. (2008) RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome. Cell Metabolism. 7(3):258-268
Lachnit, M., Kur, E., and Driever, W. (2008) Alterations of the cytoskeleton in all three embryonic lineages contribute to the epiboly defect of Pou5f1/Oct4 deficient MZspg zebrafish embryos. Developmental Biology. 315(1):1-17
Lachnit, M. (2008) Analysis of the gastrulation phenotype of pou5f1 deficient MZspg zebrafish embryos. Ph.D. Thesis. :127p
Filippi, A., Duerr, K., Ryu, S., Willaredt, M., Holzschuh, J., and Driever, W. (2007) Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and noradrenergic neuronal development. BMC Developmental Biology. 7(1):135
Webb, A.E., Sanderford, J., Frank, D., Talbot, W.S., Driever, W., and Kimelman, D. (2007) Laminin alpha5 is essential for the formation of the zebrafish fins. Developmental Biology. 311(2):369-382
Mahler, J., and Driever, W. (2007) Expression of the zebrafish intermediate neurofilament Nestin in the developing nervous system and in neural proliferation zones at postembryonic stages. BMC Developmental Biology. 7(1):89
Brockschmidt, A., Todt, U., Ryu, S., Hoischen, A., Landwehr, C., Birnbaum, S., Frenck, W., Radlwimmer, B., Lichter, P., Engels, H., Driever, W., Kubisch, C.,and Weber, R.G. (2007) Severe mental retardation with breathing abnormalities (Pitt-Hopkins syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor TCF4. Hum. Mol. Genet.. 16(12):1488-1494
Ryu, S., Mahler, J., Acampora, D., Holzschuh, J., Erhardt, S., Omodei, D., Simeone, A., and Driever, W. (2007) Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development. Current biology : CB. 17(10):873-880
Ettl, A.K. (2007) Phenotypic characterisation and genomic mapping of m865, a zebrafish mutation involved in the development of the dopaminergic system. Ph.D. Thesis.
Ledderose, J. (2007) Genetic analysis of dopaminergic systems development dopaminergic differentiation in zebrafish and rat. Ph.D. Thesis. :148p
Zecchin, E., Filippi, A., Biemar, F., Tiso, N., Pauls, S., Ellertsdottir, E., Gnugge, L., Bortolussi, M., Driever, W., and Argenton, F. (2007) Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish. Developmental Biology. 301(1):192-204
Ettl, A.K., Holzschuh, J., and Driever, W. (2006) The zebrafish mutation m865 affects formation of dopaminergic neurons and neuronal survival, and maps to a genetic interval containing the sepiapterin reductase locus. Anat. Embryol. (Berl). 211(7):73-86
Chapouton, P., Adolf, B., Leucht, C., Tannhauser, B., Ryu, S., Driever, W., Bally-Cuif, L. (2006) her5 expression reveals a pool of neural stem cells in the adult zebrafish midbrain. Development (Cambridge, England). 133(21):4293-4303
Durr, K., Holzschuh, J., Filippi, A., Ettl, A.K., Ryu, S., Shepherd, I.T., and Driever, W. (2006) Differential Roles of Transcriptional Mediator Complex Subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 During Zebrafish Retinal Development. Genetics. 174(2):693-705
Ellertsdottir, E., Ganz, J., Durr, K., Loges, N., Biemar, F., Seifert, F., Ettl, A.K., Kramer-Zucker, A.K., Nitschke, R., and Driever, W. (2006) A mutation in the zebrafish Na,K-ATPase subunit atp1a1a.1 provides genetic evidence that the sodium potassium pump contributes to left-right asymmetry downstream or in parallel to nodal flow. Developmental dynamics : an official publication of the American Association of Anatomists. 235(7):1794-1808
Ryu, S., and Driever, W. (2006) Minichromosome maintenance proteins as markers for proliferation zones during embryogenesis. Cell cycle (Georgetown, Tex.). 5(11):1140-1142
Tay, T.L., Lin, Q., Seow, T.K., Tan, K.H., Hew, C.L., and Gong, Z. (2006) Proteomic analysis of protein profiles during early development of the zebrafish, Danio rerio. Proteomics. 6(10):3176-3188
Ryu, S., Holzschuh, J., Mahler, J., and Driever, W. (2006) Genetic analysis of dopaminergic system development in zebrafish. Journal of neural transmission. Supplementum. 70:61-66
Ryu, S., Holzschuh, J., Erhardt, S., Ettl, A.K., and Driever, W. (2005) Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis. Proc. Natl. Acad. Sci. USA. 102(51):18467-18472
Simons, M., Gloy, J., Ganner, A., Bullerkotte, A., Bashkurov, M., Kronig, C., Schermer, B., Benzing, T., Cabello, O.A., Jenny, A., Mlodzik, M., Polok, B., Driever, W., Obara, T., and Walz, G. (2005) Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nature Genetics. 37(5):537-543
Filippi, A., Tiso, N., Deflorian, G., Zecchin, E., Bortolussi, M., and Argenton, F. (2005) The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord. Proc. Natl. Acad. Sci. USA. 102(12):4377-4382
Bischof, J., and Driever, W. (2004) Regulation of hhex expression in the yolk syncytial layer, the potential Nieuwkoop center homolog in zebrafish. Developmental Biology. 276(2):552-562
Gnügge, L., Meyer, D., and Driever, W. (2004) Pancreas development in zebrafish. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:531-551
Zecchin, E., Mavropoulos, A., Devos, N., Filippi, A., Tiso, N., Meyer, D., Peers, B., Bortolussi, M., Argenton, F. (2004) Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates. Developmental Biology. 268(1):174-184
Barrallo Gimeno, A., Holzschuh, J., Driever, W., and Knapik, E.W. (2004) Neural crest survival and differentiation in zebrafish depends on mont blanc/tfap2a gene function. Development (Cambridge, England). 131(7):1463-1477
Lunde, K., Belting, H.G., and Driever, W. (2004) Zebrafish pou5f1/pou2, homolog of mammalian Oct4, functions in the endoderm specification cascade. Current biology : CB. 14(1):48-55
Leung, T., Söll, I., Arnold, S.J., Kemler, R., and Driever, W. (2003) Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression. Developmental dynamics : an official publication of the American Association of Anatomists. 228(3):424-432
Onichtchouk, D., Aduroja, K., Belting, H.G., Gnügge, L., and Driever, W. (2003) Transgene driving GFP expression from the promoter of the zona pellucida gene zpc is expressed in oocytes and provides an early marker for gonad differentiation in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 228(3):393-404
Holzschuh, J., Barrallo Gimeno, A., Ettl, A.K., Durr, K., Knapik, E.W., and Driever, W. (2003) Noradrenergic neurons in the zebrafish hindbrain are induced by retinoic acid and require tfap2a for expression of the neurotransmitter phenotype. Development (Cambridge, England). 130(23):5741-5754
Gong, Z., Wan, H., Tay, T.-L., Wang, H., Chen, M., and Yan, T. (2003) Development of transgenic fish for ornamental and bioreactor by strong expression of fluorescent proteins in the skeletal muscle. Biochemical and Biophysical Research Communications. 308(1):58-63
Leung, T., Bischof, J., Söll, I., Niessing, D., Zhang, D., Ma, J., Jäckle, H., and Driever, W. (2003) bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish. Development (Cambridge, England). 130(16):3639-3649
Holzschuh, J., Hauptmann, G., and Driever, W. (2003) Genetic analysis of the roles of Hh, FGF8, and nodal signaling during catecholaminergic system development in the zebrafish brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(13):5507-5519
Lampert, J.M., Holzschuh, J., Hessel, S., Driever, W., Vogt, K., and von Lintig, J. (2003) Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis. Development (Cambridge, England). 130(10):2173-2186
Momoi, A., Yoda, H., Steinbeisser, H., Fagotto, F., Kondoh, H., Kudo, A., Driever, W., and Furutani-Seiki, M. (2003) Analysis of Wnt8 for neural posteriorizing factor by identifying Frizzled 8c and Frizzled 9 as functional receptors for Wnt8. Mechanisms of Development. 120(4):477-489
Yoda, H., Momoi, A., Esguerra, C.V., Meyer, D., Driever, W., Kondoh, H., and Furutani-Seiki, M. (2003) An expression pattern screen for genes involved in the induction of the posterior nervous system of zebrafish. Differentiation; research in biological diversity. 71(2):152-162
Tiso, N., Filippi, A., Pauls, S., Bortolussi, M., and Argenton, F. (2002) BMP signalling regulates anteroposterior endoderm patterning in zebrafish. Mechanisms of Development. 118(1-2):29-37
Biemar, F., Baraldi, F., Devos, N., Holzschuh, J., Martial, J.A., Driever, W., and Peers, B. (2002) Analysis of meis genes expression in zebrafish suggests a role in the development of organs derived from the endoderm. Developmental Biology. 247(2):495
Hauptmann, G., Belting, H.-G., Wolke, U., Lunde, K., Söll, I., Abdelilah-Seyfried, S., Prince, V., and Driever, W. (2002) spiel ohne grenzen/pou2 is required for zebrafish hindbrain segmentation. Development (Cambridge, England). 129(7):1645-1655
Biemar, F., Devos, N., Martial, J.A., Driever, W., and Peers, B. (2001) Cloning and expression of the TALE superclass homeobox Meis2 gene during zebrafish embryonic development. Mechanisms of Development. 109(2):427-431
Belting, H.G., Hauptmann, G., Meyer, D., Abdelilah-Seyfried, S., Chitnis, A., Eschbach, C., Söll, I., Thisse, C., Thisse, B., Artinger, K., Lunde, K., and Driever, W. (2001) spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development (Cambridge, England). 128(21):4165-4176
Solnica-Krezel, L. and Driever, W. (2001) The role of the homeodomain protein Bozozok in zebrafish axis formation. The International journal of developmental biology. 45(1):299-310
Holzschuh, J., Ryu, S., Aberger, F., and Driever, W. (2001) Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mechanisms of Development. 101(1-2):237-243
Biemar, F., Argenton, F., Schmidtke, R., Epperlein, S., Peers, B., and Driever, W. (2001) Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Developmental Biology. 230(2):189-203
Kim, C.H., Oda, T., Itoh, M., Jiang, D., Artinger, K.B., Chandrasekharappa, S.C., Driever, W., and Chitnis, A.B. (2000) Repressor activity of Headless/Tcf3 is essential for vertebrate head formation. Nature. 407(6806):913-916
Pogoda, H.M., Solnica-Krezel, L., Driever, W., and Meyer, D. (2000) The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of Nodal signaling required for organizer formation. Current biology : CB. 10(17):1041-1049
Saude, L., Woolley, K., Martin, P., Driever, W., and Stemple, D.L. (2000) Axis-inducing activities and cell fates of the zebrafish organizer. Development (Cambridge, England). 127(16):3407-3417
Driever, W. (2000) Developmental biology. Bringing two hearts together. Nature. 406(6792):141-142
Fekany, K., Yamanaka, Y., Leung, T., Sirotkin, H.I., Topczewski, J., Gates, M.A., Hibi, M., Renucci, A., Stemple, D., Radbill, A., Schier, A.F., Driever, W., Hirano, T., Talbot, W.S., and Solnica-Krezel, L. (1999) The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development (Cambridge, England). 126:1427-1438
Guo, S., Wilson, S.W., Cooke, S., Chitnis, A.B., Driever, W., and Rosenthal, A. (1999) Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Developmental Biology. 208:473-487
Artinger, K.B., Chitnis, A.B., Mercola, M., and Driever, W. (1999) Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons. Development (Cambridge, England). 126(18):3969-3979
Malicki, J. and Driever, W. (1999) oko meduzy mutations affect neuronal patterning in the zebrafish retina and reveal cell-cell interactions of the retinal neuroepithelial sheet. Development (Cambridge, England). 126:1235-1246
Drummond, I.A., Majumdar, A., Hentschel, H., Elger, M., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Stemple, D.L., Zwartkruis, F., Rangini, Z., Driever, W., and Fishman, M.C. (1998) Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (Cambridge, England). 125:4655-4667
Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L. (1998) Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish. Developmental Biology. 203:382-399
Raz, E., Zlokarnik, G., Tsien, R.Y., and Driever, W. (1998) ß-lactamase as a marker for gene expression in live zebrafish embryos. Developmental Biology. 203:290-294
Knapik, E.W., Goodman, A., Ekker, M., Chevrette, M., Delgado, J., Neuhauss, S., Shimoda, N., Driever, W., Fishman, M.C., and Jacob, H.J. (1998) A microsatellite genetic linkage map for zebrafish (Danio rerio). Nature Genetics. 18:338-343
Raz, E., Van Luenen, H.G.A.M., Schaerringer, B., Plasterk, R.H.A., and Driever, W. (1997) Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio. Current biology : CB. 8:82-88
Rodriguez, M. and Driever, W. (1997) Mutations resulting in transient and localized degeneration in the developing zebrafish brain. Biochemistry and cell biology = Biochimie et biologie cellulaire. 75:579-600
Abdelilah, S. and Driever, W. (1997) Pattern formation in janus-mutant zebrafish embryos. Developmental Biology. 184(1):70-84
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Schier, A.F., Neuhauss, S.C.F., Helde, K.A., Talbot, W.S., and Driever, W. (1997) The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (Cambridge, England). 124(2):327-342
Westerfield, M., E. Doerry, A.E. Kirkpatrick, W. Driever, and S.A. Douglas (1997) An on-line database for zebrafish development and genetics research. Sem. Cell Dev. Biol.. 8:477-488
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Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Abdelilah, S., Stainier, D.Y., and Driever, W. (1996) Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123:357-367
Pack, M., Solnica-Krezel, L., Malicki, J., Neuhauss, S.C., Schier, A-, F., Stemple, D.L., Driever, W., and Fishman, M.C. (1996) Mutations affecting development of zebrafish digestive organs. Development (Cambridge, England). 123:321-328
Schier, A.F., Neuhauss, S.C., Harvey, M., Malicki, J., Solnica-Krezel, L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Stemple, D.L., Rangini, Z., Yang, H., and Driever, W. (1996) Mutations affecting the development of the embryonic zebrafish brain. Development (Cambridge, England). 123:165-178
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Stainier, D.Y., Fouquet, B., Chen, J.N., Warren, K.S., Weinstein, B.M., Meiler, S.E., Mohideen, M.A., Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Driever, W., and Fishman, M.C. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123:285-292
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Weinstein, B.M., Schier, A.F., Abdelilah, S., Malicki, J., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Driever, W., and Fishman, M.C. (1996) Hematopoietic mutations in the zebrafish. Development (Cambridge, England). 123:303-309
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Driever, W. (1994) Abstracts of papers presented at the 1994 meeting on zebrafish development & genetics, April 27-May 1, 1994. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory.
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