ZFIN Lab: Section of Experimental Pathology and Toxicology

ZFIN ID: ZDB-LAB-970428-1

Section of Experimental Pathology and Toxicology

PI/Director:	Aoki, Yasunobu
Contact Person:	Amanuma, Kimiko
Email:	amanuma@nies.go.jp
URL:
Address:	Environmental Health Science Div. National Institute of Environmental Studies 16-2, Onogawa Tsukuba Ibaraki, 305 Japan
Country:	Japan
Phone:	81-298-50-2390
Fax:	81-298-50-2855
Line Designation:	ky

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 1 genomic features

STATEMENT OF RESEARCH INTERESTS

We are interested in using zf for environmental toxicology. Amanuma is now developing new transgenic zf lines intended for use in mutagenicity assay.

LAB MEMBERS

Amanuma, Kimiko Post-Doc

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Aoki, Y. (2009) Materials for zebrafish research outreach activities in national institute for environmental studies, Japan. Zebrafish. 6(2):127-132

Amanuma, K., Tone, S., Nagaya, M., Matsumoto, M., Watanabe, T., Totsuka, Y., Wakabayashi, K., and Aoki, Y. (2008) 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) and benzo[a]pyrene (BaP) in the gill and hepatopancreas of rpsL transgenic zebrafish. Mutation research. 656(1-2):36-43

Nakamura, T., Amanuma, K., Aoki, Y. (2005) Frameshift mutations induced by the acridine mustard ICR-191 in embryos and in the adult gill and hepatopancreas of rpsL transgenic zebrafish. Mutation research. 578(1-2):272-283

Amanuma, K., Nakamura, T., and Aoki, Y. (2004) MNNG-induced mutations in the adult gill and hepatopancreas and in embryos of rpsL transgenic zebrafish. Mutation research. 556(1-2):151-161

Aoki, Y., Sato, H., and Amanuma, K. (2002) Detection of environmental mutagens using transgenic animals. Bunseki Kagaku. 51(6):373-380

Amanuma, K., Tone, S., Saito, H., Shigeoka, T., and Aoki, Y. (2002) Mutational spectra of benzo[a]pyrene and MeIQx in rpsL transgenic zebrafish embryos. Mutat. Res. Genet. Toxicol. Environ. Mutagen.. 513(1-2):83-92

Ananuma, K., Takeda, H., Amanuma, H., and Aoki, Y. (2000) Transgenic zebrafish for detecting mutations caused by compounds in aquatic environments. Nat. Biotechnol.. 18(1):62-65

Mieda, M., Kikuchi, Y., Hirate, Y., Aoki, M., and Okamoto, H. (1999) Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system. Mechanisms of Development. 87(1-2):223-227

Amanuma, K., Hamada, Y., and Takeda, H. (1995) Transgene expression and integration in the zebrafish, Danio rerio. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 40:2257-2264

Matsuzaki, T., Amanuma, H., and Takeda, H. (1992) A POU-domain gene of zebrafish, ZFPOU1, specifically expressed in the developing neural tissues. Biochemical and Biophysical Research Communications. 187:1446-1453