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Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-190531-1
Vijayan Lab
PI/Director: Vijayan, Mathilakath
Contact Person: Vijayan, Mathilakath
Email: matt.vijayan@ucalgary.ca
URL: http://contacts.ucalgary.ca/info/bio/profiles/124-32886
Address: University of Calgary Biological Sciences, 210 2500 University Dr. NW Calgary, Alberta T2N 1N4
Country: Canada
Phone: 1-403-220-3094
Fax: 1 (403) 289-9311
Line Designation: ca


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS
The Vijayan Lab studies the impact of stress on the physiology and behaviour of fish. Specifically, we use zebrafish to study the impact of cortisol and corticosteroid receptor activation in regulating metabolism, behaviour, and early-life developmental programming. We have cloned and characterized both the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR) in zebrafish and have recently created knockouts for both receptors using CRISPR/Cas9 mutagenesis to study the functional significance of these receptor activation.


LAB MEMBERS
Faught, Erin Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Gauthier, P.T., Vijayan, M.M. (2019) A rapid zebrafish embryo behavioral biosensor that is capable of detecting environmental β-blockers. Environmental pollution (Barking, Essex : 1987). 250:493-502
Faught, E., Vijayan, M.M. (2019) Loss of the glucocorticoid receptor in zebrafish improves muscle glucose availability and increases growth. American journal of physiology. Endocrinology and metabolism. 316(6):E1093-E1104
Sandhu, N., Liang, L., McGeer, J., Dores, R.M., Vijayan, M.M. (2019) Cadmium disrupts melanocortin 2 receptor signaling in rainbow trout. Aquatic toxicology (Amsterdam, Netherlands). 209:26-33
Faught, E., Vijayan, M.M. (2018) The mineralocorticoid receptor is essential for stress axis regulation in zebrafish larvae. Scientific Reports. 8:18081