ZFIN Lab: Mayor Lab

ZFIN ID: ZDB-LAB-140508-1

ZFIN ID: ZDB-LAB-140508-1

Mayor Lab

PI/Director:	Mayor, Roberto
Contact Person:	Mayor, Roberto
Email:	r.mayor@ucl.ac.uk
URL:	http://www.ucl.ac.uk/cdb/research/mayor/mayor_lab/mayor_lab
Address:	University College London, Department of Cell and Developmental Biology, Gower Street, London WC1E 6BT, UK
Country:	United Kingdom
Phone:	44 0207 679 3323
Fax:	44 020 7679 7349
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

The primary aim of our research group is to elucidate the mechanism that underlies the development of the Neural Crest. We would like to know how Neural Crest cells acquire their identity within the ectoderm and how their migration and differentiation is controlled.

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Shellard, A., Szabó, A., Trepat, X., Mayor, R. (2018) Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis. Science (New York, N.Y.). 362:339-343

Alkobtawi, M., Ray, H., Barriga, E.H., Moreno, M., Kerney, R., Monsoro-Burq, A.H., Saint-Jeannet, J.P., Mayor, R. (2018) Characterization of Pax3 and Sox10 transgenic Xenopus laevis embryos as tools to study neural crest development. Developmental Biology. 444 Suppl 1:S202-S208

Bahm, I., Barriga, E.H., Frolov, A., Theveneau, E., Frankel, P., Mayor, R. (2017) PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration. Development (Cambridge, England). 144(13):2456-2468

Roycroft, A., Mayor, R. (2015) Forcing contact inhibition of locomotion. Trends in cell biology. 25:373-5

Barriga, E.H., Trainor, P.A., Bronner, M., Mayor, R. (2015) Animal models for studying neural crest development: is the mouse different?. Development (Cambridge, England). 142:1555-60

Mayor, R., and Theveneau, E. (2014) The role of the non-canonical Wnt-planar cell polarity pathway in neural crest migration. The Biochemical journal. 457(1):19-26

Barriga, E.H., Maxwell, P.H., Reyes, A.E., and Mayor, R. (2013) The hypoxia factor Hif-1alpha controls neural crest chemotaxis and epithelial to mesenchymal transition. The Journal of cell biology. 201(5):759-776

Theveneau, E., and Mayor, R. (2012) Neural crest delamination and migration: From epithelium-to-mesenchyme transition to collective cell migration. Developmental Biology. 366(1):34-54

Carmona-Fontaine, C., Matthews, H.K., Kuriyama, S., Moreno, M., Dunn, G.A., Parsons, M., Stern, C.D., and Mayor, R. (2008) Contact inhibition of locomotion in vivo controls neural crest directional migration. Nature. 456(7224):957-961

Matthews, H.K., Marchant, L., Carmona-Fontaine, C., Kuriyama, S., Larraín, J., Holt, M.R., Parsons, M., and Mayor, R. (2008) Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA. Development (Cambridge, England). 135(10):1771-1780

Blanco, M.J., Barrallo-Gimeno, A., Acloque, H., Reyes, A.E., Tada, M., Allende, M.L., Mayor, R., and Nieto, M.A. (2007) Snail1a and Snail1b cooperate in the anterior migration of the axial mesendoderm in the zebrafish embryo. Development (Cambridge, England). 134(22):4073-4081