ZFIN ID: ZDB-LAB-130226-1
China Zebrafish Resource Center (CZRC, ZKO consortium)
PI/Director: Sun, Yong-Hua
Zhu, Zuoyan
Contact Person: Sun, Yong-Hua
Email: yhsun@ihb.ac.cn
URL: http://www.zfish.cn
Address: China Zebrafish Resource Center (CZRC) 7 Donghu South Road Wuhan 430072 China
Country: China
Phone: 86 27 6878 0235
Fax: 86 27 6878 0235
Line Designation: zko


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show first 50 of 694 genomic features


STATEMENT OF RESEARCH INTERESTS
CZRC mainly focuses on collecting and maintaining the existing zebrafish line resources, developing new lines and technology, with the purpose to provide resource, technical and informatic support for Chinese and overseas zebrafish colleagues.


LAB MEMBERS
Pan, Luyuan Research Staff Li, Kuoyu Technical Staff Xie, Xunwei Technical Staff
Xiong, Feng Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Tian, J., Shao, J., Liu, C., Hou, H.Y., Chou, C.W., Shboul, M., Li, G.Q., El-Khateeb, M., Samarah, O.Q., Kou, Y., Chen, Y.H., Chen, M.J., Lyu, Z., Chen, W.L., Chen, Y.F., Sun, Y.H., Liu, Y.W. (2018) Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development. Cellular and molecular life sciences : CMLS. 76(1):163-178
Liu, J.X., Xu, Q.H., Yu, X., Zhang, T., Xie, X., Ouyang, G. (2018) Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity.. International journal of biological sciences. 14:705-716
Tao, B., Hu, H., Mitchell, K., Chen, J., Jia, H., Zhu, Z., Trudeau, V.L., Hu, W. (2018) Secretogranin-II plays a critical role in zebrafish neurovascular modeling. Journal of molecular cell biology. 10(5):388-401
Khaliq, M., Ko, S., Liu, Y., Wang, H., Sun, Y., Solnica-Krezel, L., Shin, D. (2018) Stat3 regulates liver progenitor cell-driven liver regeneration in zebrafish. Gene Expression. 18(3):157-170
Hu, H., Tao, B., Chen, J., Zhu, Z., Hu, W. (2018) Fam60al as a novel factor involved in reprogramming of somatic cell nuclear transfer in zebrafish (Danio rerio).. International journal of biological sciences. 14:78-86
Raghupathy, R.K., Zhang, X., Liu, F., Alhasani, R.H., Biswas, L., Akhtar, S., Pan, L., Moens, C.B., Li, W., Liu, M., Kennedy, B.N., Shu, X. (2017) Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish. Scientific Reports. 7:16881
Xia, H., Zhong, C., Wu, X., Chen, J., Tao, B., Xia, X., Shi, M., Zhu, Z., Trudeau, V.L., Hu, W. (2017) Mettl3 Mutation Disrupts Gamete Maturation and Reduces Fertility in Zebrafish.. Genetics. 208(2):729-743
Chen, M., Zhang, J., Pang, S., Wang, C., Wang, L., Sun, Y., Song, M., Liang, Y. (2017) Evaluating estrogenic and anti-estrogenic effect of endocrine disrupting chemicals (EDCs) by zebrafish (Danio rerio) embryo-based vitellogenin 1 (vtg1) mRNA expression. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 204:45-50
Roy, S.D., Williams, V.C., Pipalia, T.G., Li, K., Hammond, C.L., Knappe, S., Knight, R.D., Hughes, S.M. (2017) Myotome adaptability confers developmental robustness to somitic myogenesis in response to fibre number alteration. Developmental Biology. 431(2):321-335
Song, Y., Tao, B., Chen, J., Jia, S., Zhu, Z., Trudeau, V.L., Hu, W. (2017) GABAergic Neurons and Their Modulatory Effects on GnRH3 in Zebrafish. Endocrinology. 158(4):874-886
Rossi, A., Gauvrit, S., Marass, M., Pan, L., Moens, C.B., Stainier, D.Y. (2016) Regulation of Vegf signaling by natural and synthetic ligands. Blood. 128(19):2359-2366
Ma, D., Xue, Y., Zhang, Y., Sun, Y., Meng, A., Liu, F. (2016) The rising zebrafish research in China: Meeting report of the 3rd Chinese Zebrafish Principal Investigator Meeting & the Inaugural Meeting of China Zebrafish Society. Journal of genetics and genomics = Yi chuan xue bao. 43(10):617-620
Wang, H., He, L., Pei, Y., Chu, P., Huang, R., Li, Y., Liao, L., Zhu, Z., Wang, Y. (2016) Cloning and characterization of Bax1 and Bax2 genes of Ctenopharyngodon idellus and evaluation of transcript expression in response to grass carp reovirus infection. Fish physiology and biochemistry. 42(5):1369-82
Liu, L., Pan, L., Li, K., Zhang, Y., Zhu, Z., Sun, Y. (2016) Zebrafish Health Conditions in the China Zebrafish Resource Center and 20 Major Chinese Zebrafish Laboratories. Zebrafish. 13 Suppl 1:S8-S18
He, M.D., Zhang, F.H., Wang, H.L., Wang, H.P., Zhu, Z.Y., Sun, Y.H. (2015) Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos. Mutation research. 780:86-96
Pang, S.C., Wang, H.P., Zhu, Z.Y., Sun, Y.H. (2015) Transcriptional Activity and DNA Methylation Dynamics of the Gal4/UAS System in Zebrafish. Marine biotechnology (New York, N.Y.). 17(5):593-603
Huang, R., Zhu, Z., Wang, Y. (2015) LG24 and sex chromosomes. Oncotarget. 6:26543
Dai, Z., Wang, H., Jin, X., Wang, H., He, J., Liu, M., Yin, Z., Sun, Y., Lou, Q. (2015) Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish. American journal of physiology. Endocrinology and metabolism. 308(10):E849-59
Jiang, Y., He, L., Ju, C., Pei, Y., Ji, M., Li, Y., Liao, L., Jang, S., Zhu, Z., Wang, Y. (2015) Isolation and expression of grass carp toll-like receptor 5a (CiTLR5a) and 5b (CiTLR5b) gene involved in the response to flagellin stimulation and grass carp reovirus infection. Fish & shellfish immunology. 44(1):88-99
Long, L., Guo, H., Yao, D., Xiong, K., Li, Y., Liu, P., Zhu, Z., Liu, D. (2015) Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C. elegans and D. rerio. Cell Research. 25:638-41
Xie, X., Pan, L., Sun, Y. (2015) Growing with the world: rapid development of the zebrafish research in China and the China Zebrafish Resource Center. Science China. Life sciences. 58:396-9
Pan, L., Shah, A.N., Phelps, I.G., Doherty, D., Johnson, E.A., Moens, C.B. (2015) Rapid identification and recovery of ENU-induced mutations with next-generation sequencing and Paired-End Low-Error analysis. BMC Genomics. 16:83
Zhang, Y., Chen, J., Cui, X., Luo, D., Xia, H., Dai, J., Zhu, Z., Hu, W. (2015) A controllable on-off strategy for the reproductive containment of fish. Scientific Reports. 5:7614
Blasky, A.J., Pan, L., Moens, C.B., Appel, B. (2014) Pard3 regulates contact between neural crest cells and the timing of Schwann cell differentiation but is not essential for neural crest migration or myelination. Developmental dynamics : an official publication of the American Association of Anatomists. 243(12):1511-23
Lu, F.I., Sun, Y.H., Wei, C.Y., Thisse, C., Thisse, B. (2014) Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway. Nature communications. 5:5368
Pang, S.C., Wang, H.P., Li, K.Y., Zhu, Z.Y., Kang, J.X., Sun, Y.H. (2014) Double Transgenesis of Humanized fat1 and fat2 Genes Promotes Omega-3 Polyunsaturated Fatty Acids Synthesis in a Zebrafish Model. Marine biotechnology (New York, N.Y.). 16(5):580-93
Hu, B., Zhang, W., Feng, X., Ji, W., Xie, X., and Xiao, W. (2014) Zebrafish eaf1 suppresses foxo3b expression to modulate transcriptional activity of gata1 and spi1 in primitive hematopoiesis. Developmental Biology. 388(1):81-93
Quillien, A., Moore, J.C., Shin, M., Siekmann, A.F., Smith, T., Pan, L., Moens, C.B., Parsons, M.J., Lawson, N.D. (2014) Distinct Notch signaling outputs pattern the developing arterial system. Development (Cambridge, England). 141:1544-52
Wei, C.Y., Wang, H.P., Zhu, Z.Y., and Sun, Y.H. (2014) Transcriptional factors Smad1 and Smad9 act redundantly to mediate zebrafish ventral specification downstream of Smad5. The Journal of biological chemistry. 289(10):6604-18
Delaurier, A., Huycke, T.R., Nichols, J.T., Swartz, M.E., Larsen, A., Walker, C., Dowd, J., Pan, L., Moens, C.B., and Kimmel, C.B. (2014) Role of mef2ca in developmental buffering of the zebrafish larval hyoid dermal skeleton. Developmental Biology. 385(2):189-99
Tong, X., Zu, Y., Li, Z., Li, W., Ying, L., Yang, J., Wang, X., He, S., Liu, D., Zhu, Z., Chen, J., Lin, S., and Zhang, B. (2014) Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nature communications. 5:3153
Wang, Y., Pan, L., Moens, C.B., and Appel, B. (2014) Notch3 establishes brain vascular integrity by regulating pericyte number. Development (Cambridge, England). 141(2):307-317
Liu, Y., Luo, D., Zhao, H., Zhu, Z., Hu, W., and Cheng, C.H. (2013) Inheritable and Precise Large Genomic Deletions of Non-Coding RNA Genes in Zebrafish Using TALENs. PLoS One. 8(10):e76387
Xiong, F., Wei, Z.Q., Zhu, Z.Y., and Sun, Y.H. (2013) Targeted Expression in Zebrafish Primordial Germ Cells by Cre/loxP and Gal4/UAS Systems. Marine biotechnology (New York, N.Y.). 15(5):526-39
Xia, Z., Tong, X., Liang, F., Zhang, Y., Kuok, C., Zhang, Y., Liu, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish. Developmental Biology. 381(1):83-96
Alunni, A., Krecsmarik, M., Bosco, A., Galant, S., Pan, L., Moens, C.B., and Bally-Cuif, L. (2013) Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development (Cambridge, England). 140(16):3335-47
Nichols, J.T., Pan, L., Moens, C.B., and Kimmel, C.B. (2013) barx1 represses joints and promotes cartilage in the craniofacial skeleton. Development (Cambridge, England). 140(13):2765-2775
Hewamadduma, C.A., Grierson, A.J., Ma, T.P., Pan, L., Moens, C.B., Ingham, P.W., Ramesh, T., and Shaw, P.J. (2013) Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human molecular genetics. 22(12):2376-86
Wang, Y.W., Wei, C.Y., Dai, H.P., Zhu, Z.Y., and Sun, Y.H. (2013) Subtractive phage display technology identifies zebrafish marcksb that is required for gastrulation. Gene. 521(1):69-77
Zu, Y., Tong, X., Wang, Z., Liu, D., Pan, R., Li, Z., Hu, Y., Luo, Z., Huang, P., Wu, Q., Zhu, Z., Zhang, B., and Lin, S. (2013) TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nature Methods. 10(4):329-31
Liu, J.X., Zhang, D., Xie, X., Ouyang, G., Liu, X., Sun, Y., and Xiao, W. (2013) Eaf1 and Eaf2 negatively regulate canonical Wnt/β-catenin signaling. Development (Cambridge, England). 140(5):1067-1078
Choe, C.P., Collazo, A., Trinh, L.A., Pan, L., Moens, C.B., and Crump, J.G. (2013) Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. Developmental Cell. 24(3):296-309
Liu, C.W., Xiong, F., Jia, H.Z., Wang, X., Cheng, H., Sun, Y., Zhang, X.Z., Zhuo, R.X., and Feng, J. (2013) Graphene-based Anticancer Nanosystem and Its Biosafety Evaluation Using a Zebrafish Model. Biomacromolecules. 14(2):358-366
Huang, P., Zhu, Z., Lin, S., and Zhang, B. (2012) Reverse genetic approaches in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 39(9):421-433
Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M. (2012) Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Developmental Biology. 369(2):199-210
Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T.P., Huang, W., Rovira, M., Martial, J.A., Parsons, M.J., Moens, C.B., Voz, M.L., and Peers, B. (2012) Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Developmental Biology. 366(2):268-278
Delous, M., Yin, C., Shin, D., Ninov, N., Debrito Carten, J., Pan, L., Ma, T.P., Farber, S.A., Moens, C.B., and Stainier, D.Y. (2012) sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development. PLoS Genetics. 8(6):e1002754
De Rienzo, G., Bishop, J.A., Mao, Y., Pan, L., Ma, T.P., Moens, C.B., Tsai, L.H., and Sive, H. (2011) Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(12):4184-97
Taylor, R.W., Qi, J.Y., Talaga, A.K., Ma, T.P., Pan, L., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T. (2011) Asymmetric inhibition of ulk2 causes left-right differences in habenular neuropil formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(27):9869-9878
Ishtiaq Ahmed, A.S., Xiong, F., Pang, S.C., He, M.D., Waters, M.J., Zhu, Z.Y., and Sun, Y.H. (2011) Activation of GH signaling and GH-independent stimulation of growth in zebrafish by introduction of a constitutively activated GHR construct. Transgenic Research. 20(3):557-567
Osborn, D.P., Li, K., Hinits, Y., and Hughes, S.M. (2011) Cdkn1c drives muscle differentiation through a positive feedback loop with Myod. Developmental Biology. 350(2):464-475
Gao, W., Xu, L., Guan, R., Liu, X., Han, Y., Wu, Q., Xiao, Y., Qi, F., Zhu, Z., Lin, S., and Zhang, B. (2011) Wdr18 Is Required for Kupffer's Vesicle Formation and Regulation of Body Asymmetry in Zebrafish. PLoS One. 6(8):e23386
Xie, X.W., Liu, J.X., Hu, B., and Xiao, W. (2011) Zebrafish foxo3b Negatively Regulates Canonical Wnt Signaling to Affect Early Embryogenesis. PLoS One. 6(9):e24469
Dai, J., Cui, X., Zhu, Z., and Hu, W. (2010) Non-homologous end joining plays a key role in transgene concatemer formation in transgenic zebrafish embryos. International journal of biological sciences. 6(7):756-768
Xue, Y., Kuok, C., Xiao, A., Zhu, Z., Lin, S., and Zhang, B. (2010) Identification and expression analysis of mical family genes in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 37(10):685-693
Chen, C.H., Sun, Y.H., Pei, D.S., and Zhu, Z.Y. (2009) Comparative expression of zebrafish lats1 and lats2 and their implication in gastrulation movements. Developmental dynamics : an official publication of the American Association of Anatomists. 238(11):2850-2859
Pei, D.S., Sun, Y.H., and Zhu, Z.Y. (2009) Identification of a novel gene K23 over-expressed in fish cross-subfamily cloned embryos. Molecular biology reports. 36(6):1375-1380
Su, J., Yang, C., Xiong, F., Wang, Y., and Zhu, Z. (2009) Toll-like receptor 4 signaling pathway can be triggered by grass carp reovirus and Aeromonas hydrophila infection in rare minnow Gobiocypris rarus. Fish & shellfish immunology. 27(1):33-39
Luo, D., Hu, W., Chen, S., Xiao, Y., Sun, Y., and Zhu, Z. (2009) Identification of Differentially Expressed Genes Between Cloned and Zygote-Developing Zebrafish (Danio rerio) Embryos at the Dome Stage Using Suppression Subtractive Hybridization. Biology of reproduction. 80(4):674-684
Liu, J., Sun, Y.H., Wang, Y.W., Wang, N., Pei, D.S., Wang, Y.P., Hu, W., and Zhu, Z.Y. (2008) Identification of differential transcript profiles between mutual crossbred embryos of zebrafish (Danio rerio) and Chinese rare minnow (Gobiocypris rarus) by cDNA-AFLP. Theriogenology. 70(9):1525-1535
Su, J., Zhu, Z., Xiong, F., and Wang, Y. (2008) Hybrid Cytomegalovirus-U6 Promoter-based Plasmid Vectors Improve Efficiency of RNA Interference in Zebrafish. Marine biotechnology (New York, N.Y.). 10(5):511-517
Pei, D.S., Sun, Y.H., Long, Y., and Zhu, Z.Y. (2008) Inhibition of no tail (ntl) gene expression in zebrafish by external guide sequence (EGS) technique. Molecular biology reports. 35(2):139-143
Su, J., Zhu, Z., Wang, Y., Xiong, F., and Zou, J. (2008) The Cytomegalovirus Promoter-Driven Short Hairpin RNA Constructs Mediate Effective RNA Interference in Zebrafish In Vivo. Marine biotechnology (New York, N.Y.). 10(3):262-269
Pei, D.S., Sun, Y.H., Chen, C.H., Chen, S.P., Wang, Y.P., Hu, W., and Zhu, Z.Y. (2008) Identification and characterization of a novel gene differentially expressed in zebrafish cross-subfamily cloned embryos. BMC Developmental Biology. 8:29
Pei, D.S., Sun, Y.H., and Zhu, Z.Y. (2008) Construction of cytoplasmic molecular markers distinguishing Danio rerio from Gobiocypris rarus at high identity domains based on MP-PCR strategy and Sybr Green I detection. Molecular biology reports. 35(1):45-50
Pei, D.S., Sun, Y.H., Chen, S.P., Wang, Y.P., Hu, W., and Zhu, Z.Y. (2007) Identification of differentially expressed genes from the cross-subfamily cloned embryos derived from zebrafish nuclei and rare minnow enucleated eggs. Theriogenology. 68(9):1282-1291
Wang, N., Sun, Y.H., Liu, J., Wu, G., Su, J.G., Wang, Y.P., and Zhu, Z.Y. (2007) Knock down of gfp and no tail expression in zebrafish embryo by in vivo-transcribed short hairpin RNA with T7 plasmid system. Journal of Biomedical Science. 14(6):767-776
Wang, W., Liu, X., Gelinas, D., Ciruna, B., and Sun, Y. (2007) A fully automated robotic system for microinjection of zebrafish embryos. PLoS One. 2(9):e862
Liu, W.Y., Wang, Y., Qin, Y., Wang, Y.P., and Zhu, Z.Y. (2007) Site-Directed Gene Integration in Transgenic Zebrafish Mediated by Cre Recombinase Using a Combination of Mutant Lox Sites. Marine biotechnology (New York, N.Y.). 9(4):420-428
Pei, D.S., Sun, Y.H., Chen, S.P., Wang, Y.P., Hu, W., and Zhu, Z.Y. (2007) Zebrafish GAPDH can be used as a reference gene for expression analysis in cross-subfamily cloned embryos. Analytical biochemistry. 363(2):291-293
Wang, N., Sun, Y.H., Liu, J., Wang, Y.P., and Zhu, Z.Y. (2007) Molecular characterization of common carp (Cyprinus carpio) Sonic Hedgehog and discovery of its maternal expression. Development genes and evolution. 217(4):299-305
Pei, D.S., Sun, Y.H., Chen, S.P., Wang, Y.P., and Zhu, Z.Y. (2007) Cloning and characterization of cytochrome c oxidase subunit I (COXI) in Gobiocypris rarus. DNA sequence : the journal of DNA sequencing and mapping. 18(1):1-8
Liu, J., Sun, Y.H., Wang, N., Wang, Y.P., and Zhu, Z.Y. (2006) Upstream Regulatory Region of Zebrafish lunatic fringe: Isolation and Promoter Analysis. Marine biotechnology (New York, N.Y.). 8(4):357-365
Liu, W.Y., Wang, Y., Sun, Y.H., Wang, Y., Wang, Y.P., Chen, S.P., and Zhu, Z.Y. (2005) Efficient RNA interference in zebrafish embryos using siRNA synthesized with SP6 RNA polymerase. Development, growth & differentiation. 47(5):323-331