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Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-010308-3
Masai Lab
PI/Director: Masai, Ichiro
Contact Person: Masai, Ichiro
Email: masai@oist.jp
URL: http://www.oist.jp
Address: Developmental Neurobiology Unit Okinawa Institute of Science and Technology Graduate University (OIST) 1919-1 Tancha, Onna-son Okinawa 904-0495 Japan
Country: Japan
Phone: +81-(0)98-966-8523
Fax: +81-(0)98-966-2890
Line Designation: oki


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 30 genomic features


STATEMENT OF RESEARCH INTERESTS
Retinal development: neurogenesis, photoreceptor degeneration and lens development


LAB MEMBERS
Hang, Chong-Yee Post-Doc Harata, Ayano Post-Doc Nishiwaki, Yuko Post-Doc
Sugiyama, Yuki Post-Doc Takeuchi, Yuki Post-Doc Ahmed, Mai Omar Abdulrahman Graduate Student
Babu, Swathy Graduate Student Kutsia, Manana Graduate Student Ranawat, Nishtha Graduate Student
Harakuni, Tetsuya Technical Staff Kojima, Yutaka Technical Staff Liner, Jeff Technical Staff
Ward, Kimberlie Technical Staff Gima, Ayako Administrative Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Mochizuki, T., Kojima, Y., Nishiwaki, Y., Harakuni, T., Masai, I. (2018) Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish. Development (Cambridge, England). 145(20):
Iribarne, M., Masai, I. (2018) Do cGMP Levels Drive the Speed of Photoreceptor Degeneration?. Advances in experimental medicine and biology. 1074:327-333
Chandrasekhar, A., Guo, S., Masai, I., Nicolson, T., Wu, C.F. (2017) Zebrafish: from genes and neurons to circuits, behavior and disease. Journal of neurogenetics. 31:59-60
Iribarne, M., Masai, I. (2017) Neurotoxicity of cGMP in the vertebrate retina: from the initial research on rd mutant mice to zebrafish genetic approaches. Journal of neurogenetics. 31(3):88-101
Iribarne, M., Nishiwaki, Y., Nakamura, S., Araragi, M., Oguri, E., Masai, I. (2017) Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish. Scientific Reports. 7:45962
Mochizuki, T., Luo, Y.J., Tsai, H.F., Hagiwara, A., Masai, I. (2017) Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish. Development (Cambridge, England). 144:708-719
Hang, C.Y., Moriya, S., Ogawa, S., Parhar, I.S. (2016) Deep Brain Photoreceptor (val-opsin) Gene Knockout Using CRISPR/Cas Affects Chorion Formation and Embryonic Hatching in the Zebrafish. PLoS One. 11:e0165535
Imai, F., Yoshizawa, A., Matsuzaki, A., Oguri, E., Araragi, M., Nishiwaki, Y., Masai, I. (2014) Stem-loop binding protein is required for retinal cell proliferation, neurogenesis, and intraretinal axon pathfinding in zebrafish. Developmental Biology. 394(1):94-109
Mochizuki, T., Suzuki, S., Masai, I. (2014) Spatial pattern of cell geometry and cell-division orientation in zebrafish lens epithelium. Biology Open. 3(10):982-94
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T., and Masai, I. (2013) The BH3-Only SNARE BNip1 Mediates Photoreceptor Apoptosis in Response to Vesicular Fusion Defects. Developmental Cell. 25(4):374-387
Vogalis, F., Shiraki, T., Kojima, D., Wada, Y., Nishiwaki, Y., Jarvinen, J.L., Sugiyama, J., Kawakami, K., Masai, I., Kawamura, S., Fukada, Y., and Lamb,T.D. (2011) Ectopic expression of cone-specific G-protein-coupled receptor kinase GRK7 in zebrafish rods leads to lower photosensitivity and altered responses. The Journal of physiology. 589(9):2321-2348
Ohata, S., Aoki, R., Kinoshita, S., Yamaguchi, M., Tsuruoka-Kinoshita, S., Tanaka, H., Wada, H., Watabe, S., Tsuboi, T., Masai, I., and Okamoto, H. (2011) Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells. Neuron. 69(2):215-230
Imai, F., Yoshizawa, A., Fujimori-Tonou, N., Kawakami, K., and Masai, I. (2010) The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish. Development (Cambridge, England). 137(19):3257-3268
Yamaguchi, M., Imai, F., Tonou-Fujimori, N., and Masai, I. (2010) Mutations in N-cadherin and a Stardust homolog, Nagie oko, affect cell-cycle exit in zebrafish retina. Mechanisms of Development. 127(5-6):247-264
Nishiwaki, Y., Komori, A., Sagara, H., Suzuki, E., Manabe, T., Hosoya, T., Nojima, Y., Wada, H., Tanaka, H., Okamoto, H., and Masai, I. (2008) Mutation of cGMP phosphodiesterase 6alpha'-subunit gene causes progressive degeneration of cone photoreceptors in zebrafish. Mechanisms of Development. 125(11-12):932-946
Yamaguchi, M., Fujimori-Tonou, N., Yoshimura, Y., Kishi, T., Okamoto, H., and Masai, I. (2008) Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development (Cambridge, England). 135(7):1247-1257
Tanaka, H., Maeda, R., Shoji, W., Wada, H., Masai, I., Shiraki, T., Kobayashi, M., Nakayama, R., and Okamoto, H. (2007) Novel mutations affecting axon guidance in zebrafish and a role for plexin signalling in the guidance of trigeminal and facial nerve axons. Development (Cambridge, England). 134(18):3259-3269
Poggi, L., Vitorino, M., Masai, I., and Harris, W.A. (2005) Influences on neural lineage and mode of division in the zebrafish retina in vivo. The Journal of cell biology. 171(6):991-999
Yamaguchi, M., Tonou-Fujimori, N., Komori, A., Maeda, R., Nojima, Y., Li, H., Okamoto, H., and Masai, I. (2005) Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development (Cambridge, England). 32(13):3027-3043
Wada, H., Iwasaki, M., Sato, T., Masai, I., Nishiwaki, Y., Tanaka, H., Sato, A., Nojima, Y., and Okamoto, H. (2005) Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development (Cambridge, England). 132(10):2273-2285
Masai, I., Yamaguchi, M., Tonou-Fujimori, N., Komori, A., and Okamoto, H. (2005) The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development (Cambridge, England). 132(7):1539-1553
Kawakami, A., Nojima, Y., Toyoda, A., Takahoko, M., Satoh, M., Tanaka, H., Wada, H., Masai, I., Terasaki, H., Sakaki, Y., Takeda, H., and Okamoto, H. (2005) The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Current biology : CB. 15(5):480-488
Li, Q., Shirabe, K., Thisse, C., Thisse, B., Okamoto, H., Masai, I., and Kuwada, J.Y. (2005) Chemokine signaling guides axons within the retina in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25(7):1711-1717
Masai, I., Lele, Z., Yamaguchi, M., Komori, A., Nakata, A., Nishiwaki, Y., Wada, H., Tanaka, H., Nojima, Y., Hammerschmidt, M., Wilson, S.W., and Okamoto, H. (2003) N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (Cambridge, England). 130(11):2479-2494
Hamaoka, T., Takechi, M., Chinen, A., Nishiwaki, Y., and Kawamura, S. (2002) Visualization of rod photoreceptor development using GFP-transgenic zebrafish. Genesis (New York, N.Y. : 2000). 34(3):215-220
Heisenberg, C.P., Houart, C., Take-uchi, M., Rauch, G.J., Young, N., Coutinho, P., Masai, I., Caneparo, L., Concha, M.L., Geisler, R., Dale, T.C., Wilson, S.W., and Stemple, D.L. (2001) A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes & Development. 15(11):1427-1434
Masai, I., Stemple, D.L., Okamoto, H., and Wilson, S.W. (2000) Midline signals regulate retinal neurogenesis in zebrafish. Neuron. 27(2):251-263
Masai, I., Heisenberg, C.P., Barth, K.A., Macdonald, R., Adamek, S., and Wilson, S.W. (1997) floating head and masterblind regulate neuronal patterning in the roof of the forebrain. Neuron. 18(1):43-57
Wilson, S., Barth, K.A., Masai, I., and Macdonald, R. (1996) Genes involved in neuronal specification at boundary zones in the embryonic zebrafish forebrain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 14:65