fluticasone propionate

Term ID

CHEBI:31441

Synonyms

6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl propanoate
Cutivate
Fluticasone propionate

Definition

A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl substituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity.

References

Beilstein:6944704
CAS:80474-14-2
DrugBank:DB00588
Drug_Central:1225
KEGG:D01708
Patent:NL8100707
Patent:US4335121
Reaxys:6944704
Wikipedia:Fluticasone_Propionate

Ontology

ChEBI ( EBI )

Relationships

is a type of: 3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid corticosteroid fluorinated steroid propanoate ester ... Show All 7 Terms

3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid corticosteroid fluorinated steroid propanoate ester steroid ester thioester Show first 5 Terms
has_functional_parent: fluticasone

fluticasone Show first 5 Terms
has_parent_hydride: androstane

androstane Show first 5 Terms
has_role: adrenergic agent anti-allergic agent anti-asthmatic drug anti-inflammatory drug bronchodilator agent ... Show All 6 Terms

adrenergic agent anti-allergic agent anti-asthmatic drug anti-inflammatory drug bronchodilator agent dermatologic drug Show first 5 Terms

Phenotype

Phenotype resulting from fluticasone propionate

Phenotype where environments contain fluticasone propionate

Phenotype modified by environments containing fluticasone propionate

Human Disease / Model Data