header logo image header logo text
Downloads Login
Research
General Information
ZIRC
OBO ID: GO:1990306
Term Name: RSP5-BUL ubiquitin ligase complex Search Ontology:
Synonyms:
  • RSP5-BUL1 complex
  • RSP5-BUL2 complex
Definition: A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.9931424
References:
  • IntAct:EBI-9105217
  • IntAct:EBI-9105295
Ontology: GO: Cellular Component   QuickGO   AmiGO
EXPRESSION No data available
PHENOTYPE No data available