OBO ID: GO:0099126
Term Name: transforming growth factor beta complex Search Ontology:
Synonyms:
  • TGF-beta complex
  • TGF-beta dimer
  • TGFB complex
  • TGFB dimer
  • TGFbeta complex
  • TGFbeta dimer
Definition: A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP. 22943793
References:
  • IntAct:EBI-12501958
  • IntAct:EBI-12502251
  • IntAct:EBI-12502440
Ontology: GO: Cellular Component   QuickGO   AmiGO
EXPRESSION No data available
PHENOTYPE No data available