| OBO ID: GO:0097071 |
| Term Name: | interferon regulatory factor complex | Search Ontology: | |
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| Definition: | A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. 20043992 | ||
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| Ontology: | GO: Cellular Component QuickGO AmiGO |
Show first 5 Terms
EXPRESSION
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PHENOTYPE
No data available