| Term Name: |
obsolete adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate |
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Search Ontology:
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| Synonyms: |
- activation of funny current by beta-adrenergic receptor signaling pathway
- adenylate cyclase-activating cardiac adrenergic receptor signaling pathway
- adrenergic receptor signaling pathway involved in positive regulation of heart rate
- adrenergic receptor signalling pathway involved in positive regulation of heart rate
- beta adrenergic receptor signaling pathway involved in positive regulation of heart rate
- Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate
- If activation by beta-adrenergic receptor signaling pathway
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| Definition: |
OBSOLETE. An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.
21099118
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| References: |
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| Ontology: |
GO: Biological Process
QuickGO
AmiGO
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| Obsolete: |
true |
