OBO ID: GO:0071159 |
Term Name: | NF-kappaB complex | Search Ontology: | |
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Definition: | A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. 0849327946 | ||
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Ontology: | GO: Cellular Component QuickGO AmiGO |
EXPRESSION
No data available
PHENOTYPE
No data available