Term Name: |
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay |
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Search Ontology:
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Synonyms: |
- 3'-5' NMD
- 3'-5' nonsense-mediated decay
- 3'-5' nonsense-mediated mRNA decay
- nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay
- nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay
- nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
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Definition: |
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
12769863
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References: |
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Ontology: |
GO: Biological Process
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