OBO ID: GO:0062079 |
Term Name: | ATG2-ATG18 complex | Search Ontology: | |
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Definition: | A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae. 23230146 | ||
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Ontology: | GO: Cellular Component QuickGO AmiGO |
EXPRESSION
No data available
PHENOTYPE
No data available