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ubiquitin protein ligase activity
APC-Cdc20 complex activity
APC-fizzy related complex activity
E3 involved in endoplasmic reticulum-associated degradation
ER-associated E3 ligase
protein ubiquitination activity
ubiquitin ligase activity involved in ER-associated degradation pathway
ubiquitin protein ligase activity involved in chloroplast disassembly
ubiquitin protein ligase activity involved in ER-associated degradation pathway
ubiquitin protein ligase activity involved in ERAD pathway
ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.22863777