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ZIRC
OBO ID: GO:0045047
Term Name: protein targeting to ER Search Ontology:
Synonyms:
  • protein targeting to endoplasmic reticulum
  • protein-endoplasmic reticulum targeting
  • protein-ER targeting
Definition: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. 0716731363
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available