OBO ID: GO:0045003
Term Name: double-strand break repair via synthesis-dependent strand annealing Search Ontology:
  • mitotic gene conversion
  • SDSA
Definition: SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. 10357855
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available