OBO ID: GO:0039530 |
Term Name: | MDA-5 signaling pathway | Search Ontology: | |
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Definition: | The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. (2) | ||
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Ontology: | GO: Biological Process QuickGO AmiGO |
PHENOTYPE
No data available