OBO ID: GO:0036317
Term Name: tyrosyl-RNA phosphodiesterase activity Search Ontology:
Synonyms:
  • unlinkase activity
  • uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity
  • VPg unlinkase activity
  • Y-pUpN PDE activity
Definition: Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. (2)
References:
Ontology: GO: Molecular Function    QuickGO    AmiGO
PHENOTYPE No data available