OBO ID: GO:0035329 |
Term Name: | hippo signaling | Search Ontology: | |
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Definition: | An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation. (3) | ||
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Ontology: | GO: Biological Process QuickGO AmiGO |