OBO ID: GO:0031511
Term Name: Mis6-Sim4 complex Search Ontology:
Synonyms:
  • Mcm21
  • Mis6 centromere subcomplex
  • Mis6-Mal2-Sim4 centromere complex
  • Sim4 complex
Definition: A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human. (2)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available