| OBO ID: GO:0030122 |
| Term Name: | AP-2 adaptor complex | Search Ontology: | |
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| Definition: | A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). (4) | ||
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| Ontology: | GO: Cellular Component QuickGO AmiGO |
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EXPRESSION
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PHENOTYPE
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