Term Name: |
heparan sulfate proteoglycan biosynthetic process |
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Search Ontology:
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Synonyms: |
- heparan sulfate proteoglycan anabolism
- heparan sulfate proteoglycan biosynthesis
- heparan sulfate proteoglycan formation
- heparan sulfate proteoglycan synthesis
- heparan sulphate proteoglycan biosynthesis
- heparan sulphate proteoglycan biosynthetic process
- heparin proteoglycan biosynthetic process
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Definition: |
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
(2)
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References: |
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Ontology: |
GO: Biological Process
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AmiGO
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