OBO ID: GO:0007252
Term Name: I-kappaB phosphorylation Search Ontology:
  • IkappaB phosphorylation
  • IKB phosphorylation
  • inhibitor of kappaB phosphorylation
  • inhibitor of NF-kappaB phosphorylation
Definition: The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. (2)
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available