|OBO ID: GO:0007186|
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|Term Name:||G protein-coupled receptor signaling pathway||Search Ontology:|
|Definition:||A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. (3)|
|Ontology:||GO: Biological Process QuickGO AmiGO|
|is a type of:||
|negatively regulated by:||
|positively regulated by:||
PHENOTYPE No data available