ZFIN GO: Biological Process: G protein-coupled receptor signaling pathway

OBO ID: GO:0007186

Term Name:	G protein-coupled receptor signaling pathway		Search Ontology:
Synonyms:	dimeric G-protein coupled receptor signaling pathway dimeric G-protein coupled receptor signalling pathway G protein coupled receptor protein signaling pathway G protein coupled receptor protein signalling pathway G-protein coupled receptor protein signal transduction G-protein coupled receptor protein signaling pathway G-protein coupled receptor signaling pathway via GPCR dimer G-protein coupled receptor signalling pathway G-protein-coupled receptor protein signalling pathway GPCR signaling pathway GPCR signalling pathway
Definition:	The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. (3)
References:
Ontology:	GO: Biological Process QuickGO AmiGO

Relationships

has parts:	G protein-coupled receptor activity ion channel regulator activity involved in G protein-coupled receptor signaling pathway potassium channel activator activity involved in G protein-coupled receptor signaling pathway G protein-coupled receptor activity ion channel regulator activity involved in G protein-coupled receptor signaling pathway potassium channel activator activity involved in G protein-coupled receptor signaling pathway Show first 5 Terms
is a type of:	signal transduction signal transduction Show first 5 Terms
has subtype:	adenylate cyclase-modulating G protein-coupled receptor signaling pathway adrenergic receptor signaling pathway angiotensin-activated signaling pathway apelin receptor signaling pathway bombesin receptor signaling pathway ... Show All 41 Terms adenylate cyclase-modulating G protein-coupled receptor signaling pathway adrenergic receptor signaling pathway angiotensin-activated signaling pathway apelin receptor signaling pathway bombesin receptor signaling pathway calcitonin family receptor signaling pathway cannabinoid signaling pathway chemokine-mediated signaling pathway cholecystokinin signaling pathway complement component C5a signaling pathway endothelin receptor signaling pathway follicle-stimulating hormone signaling pathway G protein-coupled acetylcholine receptor signaling pathway G protein-coupled chemorepellent receptor signaling pathway G protein-coupled glutamate receptor signaling pathway G protein-coupled opioid receptor signaling pathway G protein-coupled purinergic receptor signaling pathway G protein-coupled receptor signaling pathway involved in dauer larval development G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium G protein-coupled receptor signaling pathway involved in heart process G protein-coupled receptor signaling pathway involved in social behavior G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger G protein-coupled serotonin receptor signaling pathway gastric inhibitory peptide signaling pathway ion channel modulating, G protein-coupled receptor signaling pathway leukotriene signaling pathway luteinizing hormone signaling pathway neuropeptide signaling pathway octopamine or tyramine signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-inhibiting G protein-coupled receptor signaling pathway phospholipase D-activating G protein-coupled receptor signaling pathway potassium channel activating, G protein-coupled receptor signaling pathway protein kinase C-activating G protein-coupled receptor signaling pathway rhodopsin mediated signaling pathway somatostatin receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway tachykinin receptor signaling pathway thrombin-activated receptor signaling pathway thromboxane A2 signaling pathway thyroid-stimulating hormone signaling pathway Show first 5 Terms
negatively regulated by:	negative regulation of G protein-coupled receptor signaling pathway negative regulation of G protein-coupled receptor signaling pathway Show first 5 Terms
positively regulated by:	positive regulation of G protein-coupled receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway Show first 5 Terms
regulated by:	regulation of G protein-coupled receptor signaling pathway regulation of G protein-coupled receptor signaling pathway Show first 5 Terms

PHENOTYPE No data available