OBO ID: GO:0006601
Term Name: creatine biosynthetic process Search Ontology:
Synonyms:
  • creatine anabolism
  • creatine biosynthesis
  • creatine formation
  • creatine synthesis
Definition: The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.
References:
Ontology: GO: Biological Process    QuickGO    AmiGO
PHENOTYPE No data available