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GPI anchor biosynthetic process
glycosylphosphatidylinositol biosynthetic process
GPI anchor anabolism
GPI anchor biosynthesis
GPI anchor formation
GPI anchor synthesis
GPI/GSI anchor biosynthesis
GPI/GSI anchor biosynthetic process
The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.0198547684